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GPI [ficolin-1-rich granule lumen]
Stable Identifier
R-HSA-6801506
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
ficolin-1-rich granule lumen
Synonyms
Glucose-6-phosphate isomerase , Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI, Neuroleukin, NLK, Sperm antigen-36, SA-36
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of ficolin-rich granule lumen proteins (Homo sapiens)
Ficolin-rich granule lumen proteins [ficolin-1-rich granule lumen] (Homo sapiens)
GPI [ficolin-1-rich granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P06744 GPI
Gene Names
GPI
Chain
initiator methionine:, chain:2-558
Reference Genes
BioGPS Gene:2821 GPI
COSMIC (genes):GPI GPI
CTD Gene:2821 GPI
dbSNP Gene:2821 GPI
ENSEMBL:ENSG00000105220 GPI
HGNC:4458 GPI
KEGG:hsa:2821 GPI
Monarch:2821 GPI
NCBI Gene:2821 GPI
OMIM:172400 GPI
UCSC:P06744 GPI
Reference Transcript
RefSeq:NM_001329909.1 GPI
RefSeq:NM_001329911.1 GPI
RefSeq:NM_000175.4 GPI
RefSeq:NM_001184722.1 GPI
RefSeq:NM_001329910.1 GPI
Other Identifiers
11755817_s_at
16860709
208308_PM_s_at
208308_s_at
2821
3829688
3829689
3829690
3829691
3829692
3829694
3829695
3829696
3829698
3829699
3829700
3829701
3829703
3829704
3829705
3829715
3829716
3829717
3829718
3829719
3829720
3829721
3829722
3829723
3829724
3829725
3829726
3829727
3829728
3829729
3829730
3829731
3829732
3829733
3829734
3829735
3829736
3829737
3829738
3829739
3829740
3829741
3829742
3829743
3829744
3829745
3829750
3829752
3829753
3829754
39122_at
8027621
88482_at
A_14_P128352
A_24_P108451
GE57542
GE86825
GE88500
GO:0001701
GO:0001707
GO:0002376
GO:0002639
GO:0003824
GO:0004347
GO:0005125
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005829
GO:0005886
GO:0005975
GO:0006002
GO:0006091
GO:0006094
GO:0006096
GO:0006959
GO:0007165
GO:0007599
GO:0007611
GO:0008083
GO:0010595
GO:0016020
GO:0016853
GO:0031625
GO:0032355
GO:0032570
GO:0033574
GO:0034101
GO:0034774
GO:0035902
GO:0035994
GO:0042593
GO:0043226
GO:0043524
GO:0046686
GO:0048018
GO:0048029
GO:0048856
GO:0050877
GO:0051156
GO:0055086
GO:0060170
GO:0070062
GO:0097367
GO:0098772
GO:1901135
GO:1904813
HMNXSV003002225
ILMN_2173451
K03515_at
PH_hs_0019281
TC19000442.hg
g4504086_3p_s_at
Participates
as a member of
Ficolin-rich granule lumen proteins [ficolin-1-rich granule lumen] (Homo sapiens)
Other forms of this molecule
GPI [extracellular region]
GPI [secretory granule lumen]
GPI [cytosol]
Inferred To
gpib [ficolin-1-rich granule lumen]
(Danio rerio)
gpi [ficolin-1-rich granule lumen]
(Dictyostelium discoideum)
gpi [ficolin-1-rich granule lumen]
(Xenopus tropicalis)
Pgi [ficolin-1-rich granule lumen]
(Drosophila melanogaster)
gpi-1 [ficolin-1-rich granule lumen]
(Caenorhabditis elegans)
GPI [ficolin-1-rich granule lumen]
(Bos taurus)
GPI [ficolin-1-rich granule lumen]
(Canis familiaris)
GPI [ficolin-1-rich granule lumen]
(Gallus gallus)
GPI [ficolin-1-rich granule lumen]
(Mus musculus)
GPI [ficolin-1-rich granule lumen]
(Plasmodium falciparum)
GPI [ficolin-1-rich granule lumen]
(Rattus norvegicus)
GPI [ficolin-1-rich granule lumen]
(Saccharomyces cerevisiae)
GPI [ficolin-1-rich granule lumen]
(Schizosaccharomyces pombe)
GPI [ficolin-1-rich granule lumen]
(Sus scrofa)
Cross References
RefSeq
NP_001171651.1
,
NP_001316839.1
,
NP_001316838.1
,
NP_000166.2
,
NP_001316840.1
ENSEMBL
ENST00000356487
,
ENSP00000465858
,
ENSP00000348877
,
ENST00000588991
OpenTargets
ENSG00000105220
HPA
ENSG00000105220-GPI
PRO
P06744
Pharos - Targets
P06744
GlyGen
P06744
Orphanet
GPI
HMDB Protein
HMDBP00806
PDB
6XUI
,
6XUH
,
1IAT
,
1IRI
,
1JIQ
,
1NUH
,
1JLH
,
8P2K
,
8BBH
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P10636-8 MAPT
3
MAPT-8 [cytosol]
(R-HSA-9619519)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
0.569
7
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.483
6
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