Reactome | GSTP1 [secretory granule lumen]

GSTP1 [secretory granule lumen]

Stable Identifier

R-HSA-6801488

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

secretory granule lumen

Synonyms

Glutathione S-transferase pi 1

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P09211 GSTP1

Gene Names

GSTP1, FAEES3, GST3

Chain

initiator methionine:, chain:2-210

Reference Genes

BioGPS Gene:2950 GSTP1

COSMIC (genes):GSTP1 GSTP1

CTD Gene:2950 GSTP1

dbSNP Gene:2950 GSTP1

ENSEMBL:ENSG00000084207 GSTP1

HGNC:4638 GSTP1

KEGG:hsa:2950 GSTP1

Monarch:2950 GSTP1

NCBI Gene:2950 GSTP1

OMIM:134660 GSTP1

UCSC:P09211 GSTP1

Reference Transcript

RefSeq:NM_000852.3 GSTP1

Other Identifiers

11715344_at

16727919

200824_3p_at

200824_PM_at

200824_at

2950

3337175

3337176

3337177

3337178

3337179

3337180

3337181

3337182

3337183

3337184

3337185

3337186

3337187

3337188

3337189

3337190

3337191

3337192

3337193

33396_at

7941936

829_s_at

A_14_P107175

A_14_P109888

A_23_P202658

GO:0000302

GO:0002674

GO:0003824

GO:0004364

GO:0004602

GO:0005504

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005737

GO:0005739

GO:0005829

GO:0006469

GO:0006575

GO:0006629

GO:0006693

GO:0006749

GO:0006790

GO:0006805

GO:0007417

GO:0008289

GO:0008432

GO:0009890

GO:0010804

GO:0016209

GO:0016491

GO:0016740

GO:0019207

GO:0031982

GO:0032691

GO:0032720

GO:0032872

GO:0032873

GO:0032930

GO:0034774

GO:0035726

GO:0035730

GO:0035731

GO:0035732

GO:0043066

GO:0043124

GO:0043226

GO:0043407

GO:0043409

GO:0043508

GO:0043651

GO:0048147

GO:0048856

GO:0051122

GO:0051771

GO:0070026

GO:0070062

GO:0070372

GO:0070373

GO:0070664

GO:0071222

GO:0071638

GO:0097057

GO:0098754

GO:0098772

GO:0098869

GO:1901687

GO:1904813

GO:2001237

HMNXSV003039809

ILMN_1679809

M24485_s_at

PH_hs_0019546

PH_hs_0035926

TC11000694.hg

U21689_at

g6552334_3p_at

g6552334_3p_s_at

g6552334_3p_x_at

Participates

as a member of

Secretory granule lumen proteins [secretory granule lumen] (Homo sapiens)

Other forms of this molecule

GSTP1 [ficolin-1-rich granule lumen]

GSTP1 [extracellular region]

GSTP1 [cytosol]

Inferred To

LOC100739163 [secretory granule lumen] (Sus scrofa)

Homologues of GSTP1 [secretory granule lumen] (Bos taurus)

Homologues of GSTP1 [secretory granule lumen] (Canis familiaris)

Homologues of GSTP1 [secretory granule lumen] (Dictyostelium discoideum)

Homologues of GSTP1 [secretory granule lumen] (Mus musculus)

GSTP1 [secretory granule lumen] (Bos taurus)

GSTP1 [secretory granule lumen] (Caenorhabditis elegans)

GSTP1 [secretory granule lumen] (Canis familiaris)

GSTP1 [secretory granule lumen] (Dictyostelium discoideum)

GSTP1 [secretory granule lumen] (Mus musculus)

GSTP1 [secretory granule lumen] (Plasmodium falciparum)

GSTP1 [secretory granule lumen] (Rattus norvegicus)

gstp1.2 [secretory granule lumen] (Danio rerio)

LOC101730710 [secretory granule lumen] (Xenopus tropicalis)

Cross References

OpenTargets

ENSG00000084207

ENSEMBL

ENSP00000381607, ENST00000398606, ENSG00000084207

ZINC - FDA approved

GSTP1_HUMAN

ZINC - Substances

GSTP1_HUMAN

ZINC - Biogenic

GSTP1_HUMAN

ZINC target

P09211

PRO

P09211

GlyGen

P09211

PDB

1MD3, 1MD4, 5DJM, 5DJL, 8GSS, 6Y1E, 1PX6, 3GUS, 1GSS, 3KMO, 13GS, 4PGT, 3IE3, 2J9H, 2GSS, 6GSS, 5JCW, 1ZGN, 6LLX, 1EOG, 5DAL, 5L6X, 1AQV, 2PGT, 16GS, 12GS, 7GSS, 14GS, 3CSI, 6AP9, 2A2R, 4GSS, 20GS, 22GS, 3PGT, 3GSS, 1PX7, 3KMN, 19GS, 9GSS, 5GSS, 17GS, 5DAK, 7XBA, 1KBN, 3KM6, 3N9J, 5J41, 3HJM, 1PGT, 5X79, 2A2S, 3HKR, 11GS, 1EOH, 3DGQ, 5DCG, 3DD3, 3CSJ, 1AQW, 18GS, 1AQX, 3CSH, 10GS, 1LBK, 5DDL, 7BIA, 3HJO

ZINC - Metabolites

GSTP1_HUMAN

HPA

ENSG00000084207-GSTP1

GeneCards

GSTP1

Pharos - Targets

P09211

ZINC - Predictions - Purchasable

GSTP1_HUMAN

HMDB Protein

HMDBP00834

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q12933 TRAF2	5	TRAF2 [cytosol] (R-HSA-66370) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) TRAF2 [nucleoplasm] (R-HSA-8862199)	0.68	5
UniProt:P0DPK4 NOTCH2NLC	1	NOTCH2NLC [extracellular region] (R-HSA-9908932)	0.556	3
UniProt:Q7Z3S9 NOTCH2NLA	3	NOTCH2NLA [extracellular region] (R-HSA-9908935) NOTCH2NLA(1-?) [extracellular region] (R-HSA-9911493) NOTCH2NLA(?-236) [extracellular region] (R-HSA-9911490)	0.556	3
UniProt:P22735 TGM1	3	TGM1 [cytosol] (R-HSA-6813756) TGM1 [cornified envelope] (R-HSA-8847706) TGM1 [plasma membrane] (R-HSA-6813757)	0.556	3
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	3
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	12

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