Reactome | CSTB [ficolin-1-rich granule lumen]

CSTB [ficolin-1-rich granule lumen]

Stable Identifier

R-HSA-6801376

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

ficolin-1-rich granule lumen

Synonyms

Cystatin-B, CYTB_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P04080 CSTB

Gene Names

CSTB, CST6, STFB

Chain

chain:1-98

Reference Genes

BioGPS Gene:1476 CSTB

COSMIC (genes):CST6 CSTB

COSMIC (genes):CSTB CSTB

CTD Gene:1476 CSTB

dbSNP Gene:1476 CSTB

ENSEMBL:ENSG00000160213 CSTB

HGNC:2482 CSTB

KEGG:hsa:1476 CSTB

Monarch:1476 CSTB

NCBI Gene:1476 CSTB

OMIM:601145 CSTB

UCSC:P04080 CSTB

Reference Transcript

RefSeq:NM_000100.3 CSTB

Other Identifiers

11728320_a_at

11754056_x_at

11757287_x_at

11758318_s_at

1476

16926253

201201_PM_at

201201_at

236449_PM_at

236449_at

35816_at

3934246

3934247

3934248

3934249

3934250

3934251

3934252

3934253

3934254

3934257

3934258

47032_at

8070701

A_23_P154894

GE54961

GE85822

GO:0002020

GO:0003723

GO:0004866

GO:0004869

GO:0005576

GO:0005615

GO:0005634

GO:0005730

GO:0005737

GO:0005829

GO:0008344

GO:0010466

GO:0030312

GO:0031012

GO:0034774

GO:0043226

GO:0045861

GO:0062023

GO:0070062

GO:0098772

GO:1904724

GO:1904813

GO:1990000

HMNXSV003016324

Hs.49031.0.A1_3p_at

ILMN_1761797

PH_hs_0000080

TC21000509.hg

U46692_rna1_at

g4503116_3p_at

Participates

as a member of

Ficolin-rich granule lumen proteins [ficolin-1-rich granule lumen] (Homo sapiens)

Other forms of this molecule

CSTB [tertiary granule lumen]

CSTB [extracellular region]

CSTB [secretory granule lumen]

Inferred To

cst14b.1 [ficolin-1-rich granule lumen] (Danio rerio)

cst14a.1 [ficolin-1-rich granule lumen] (Danio rerio)

cst14a.2 [ficolin-1-rich granule lumen] (Danio rerio)

CSTB [ficolin-1-rich granule lumen] (Bos taurus)

CSTB [ficolin-1-rich granule lumen] (Canis familiaris)

CSTB [ficolin-1-rich granule lumen] (Gallus gallus)

CSTB [ficolin-1-rich granule lumen] (Sus scrofa)

cstb [ficolin-1-rich granule lumen] (Xenopus tropicalis)

cpiA [ficolin-1-rich granule lumen] (Dictyostelium discoideum)

cpiB [ficolin-1-rich granule lumen] (Dictyostelium discoideum)

cpiC [ficolin-1-rich granule lumen] (Dictyostelium discoideum)

Homologues of CSTB [ficolin-1-rich granule lumen] (Danio rerio)

Homologues of CSTB [ficolin-1-rich granule lumen] (Dictyostelium discoideum)

Homologues of CSTB [ficolin-1-rich granule lumen] (Xenopus tropicalis)

LOC116408737 [ficolin-1-rich granule lumen] (Xenopus tropicalis)

Cstb [ficolin-1-rich granule lumen] (Mus musculus)

Cstb [ficolin-1-rich granule lumen] (Rattus norvegicus)

Cross References

ENSEMBL

ENST00000291568, ENSP00000291568

OpenTargets

ENSG00000160213

HPA

ENSG00000160213-CSTB

PRO

P04080

Pharos - Targets

P04080

GlyGen

P04080

Orphanet

CSTB

PDB

2OCT, 4N6V, 1STF

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.615	12

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