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ITGAX [secretory granule membrane]
Stable Identifier
R-HSA-6801289
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
secretory granule membrane
Synonyms
Integrin alpha-X, ITAX_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of secretory granule membrane proteins (Homo sapiens)
Secretory granule membrane proteins [secretory granule membrane] (Homo sapiens)
ITGAX [secretory granule membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P20702 ITGAX
Gene Names
ITGAX, CD11C
Chain
signal peptide:1-19, chain:20-1163
Reference Genes
BioGPS Gene:3687 ITGAX
COSMIC (genes):ITGAX ITGAX
CTD Gene:3687 ITGAX
dbSNP Gene:3687 ITGAX
ENSEMBL:ENSG00000140678 ITGAX
HGNC:6152 ITGAX
KEGG Gene (Homo sapiens):3687 ITGAX
Monarch:3687 ITGAX
NCBI Gene:3687 ITGAX
OMIM:151510 ITGAX
UCSC:P20702 ITGAX
Reference Transcript
RefSeq:NM_000887.4 ITGAX
RefSeq:NM_001286375.1 ITGAX
Other Identifiers
0001500086
11743475_a_at
11750033_a_at
11761777_x_at
16818272
210184_PM_at
210184_at
3657010
3657042
3657043
3657047
3657049
3657052
3657053
3657057
3657058
3657059
3657060
3657062
3657063
3657065
3657066
3657067
3657068
3657069
3657070
3657071
3657072
3657078
3657079
3657081
3657084
3657085
3657086
3657087
3657088
3657089
3657090
3657092
3657094
3657096
3657097
3657098
3657099
3657100
3657101
3657102
3657103
3657104
3657106
3657153
36709_at
3687
48209_s_at
52349_s_at
58878_s_at
7995128
A_14_P127914
A_24_P344251
GE58097
GO:0002376
GO:0003674
GO:0005178
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005886
GO:0006950
GO:0007155
GO:0007160
GO:0007165
GO:0007229
GO:0008150
GO:0008283
GO:0008284
GO:0008305
GO:0009887
GO:0009897
GO:0009986
GO:0010628
GO:0016020
GO:0016021
GO:0019899
GO:0030335
GO:0030667
GO:0030971
GO:0031410
GO:0031643
GO:0032991
GO:0033627
GO:0034113
GO:0034689
GO:0038023
GO:0040011
GO:0043167
GO:0043226
GO:0045766
GO:0046872
GO:0048646
GO:0048856
GO:0048870
GO:0050877
GO:0051607
GO:0070821
GO:0098609
GO:0101003
GO:1905956
HMNXSV003047066
ILMN_1717796
ILMN_1726175
ILMN_1730176
ILMN_2254635
M81695_s_at
PH_hs_0024365
TC16000375.hg
Participates
as a member of
Secretory granule membrane proteins [secretory granule membrane] (Homo sapiens)
Other forms of this molecule
ITGAX [tertiary granule membrane]
ITGAX [ficolin-1-rich granule membrane]
ITGAX [plasma membrane]
Inferred To
ItgaPS5 [secretory granule membrane]
(Drosophila melanogaster)
scb [secretory granule membrane]
(Drosophila melanogaster)
ITGAM [secretory granule membrane]
(Sus scrofa)
LOC101731775 [secretory granule membrane]
(Xenopus tropicalis)
Itgax [secretory granule membrane]
(Mus musculus)
Itgax [secretory granule membrane]
(Rattus norvegicus)
itgam.1 [secretory granule membrane]
(Danio rerio)
ITGAX [secretory granule membrane]
(Bos taurus)
Homologues of ITGAX [secretory granule membrane]
(Drosophila melanogaster)
ITGAD [secretory granule membrane]
(Gallus gallus)
ItgaPS4 [secretory granule membrane]
(Drosophila melanogaster)
Cross References
RefSeq
NP_001273304.1
,
NP_000878.2
Guide to Pharmacology - Targets
2454
OpenTargets
ENSG00000140678
HPA
ENSG00000140678-ITGAX
GeneCards
P20702
Ensembl
ENSG00000140678
,
ENST00000268296
,
ENSP00000268296
PRO
P20702
Pharos - Targets
P20702
Orphanet
24633
PDB
4NEN
,
1N3Y
,
3K6S
,
4NEH
,
2LUV
,
5ES4
,
3K71
,
3K72
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