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CR1 [ficolin-1-rich granule membrane]
Stable Identifier
R-HSA-6801286
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
ficolin-1-rich granule membrane
Synonyms
Complement receptor type 1, CR1_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of ficolin-rich granule membrane proteins (Homo sapiens)
Ficolin-rich granule membrane proteins [ficolin-1-rich granule membrane] (Homo sapiens)
CR1 [ficolin-1-rich granule membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P17927 CR1
Gene Names
CR1, C3BR
Chain
signal peptide:1-41, chain:42-2039
Reference Genes
BioGPS Gene:1378 CR1
COSMIC (genes):CR1 CR1
CTD Gene:1378 CR1
dbSNP Gene:1378 CR1
ENSEMBL:ENSG00000203710 CR1
ENSEMBL_homo_sapiens_GENE:ENSG00000203710.12 CR1
HGNC:2334 CR1
KEGG Gene (Homo sapiens):1378 CR1
Monarch:1378 CR1
NCBI Gene:1378 CR1
OMIM:120620 CR1
UCSC:P17927 CR1
Reference Transcript
RefSeq:NM_000651.4 CR1
RefSeq:NM_000573.3 CR1
Other Identifiers
11733587_a_at
11747196_s_at
1378
16676819
206244_PM_at
206244_at
208488_PM_s_at
208488_s_at
217552_3p_x_at
217552_PM_x_at
217552_x_at
2377334
2377335
2377336
2377342
2377343
2377346
2377347
2377350
2377351
2377352
2377353
2377355
2377356
2377357
2377358
2377360
2377361
2377362
2377363
2377365
2377366
2377367
2377369
2377370
2377371
2377372
2377374
2377375
2377376
2377377
2377378
2377379
2377380
2377381
2377382
2377384
2377385
2377388
2377389
2377390
2377391
2377392
2377393
2377394
2377395
2377396
2377397
2377398
2377402
2377403
2377404
2377405
2377407
2377408
2377409
2377410
2377411
2377412
2377413
2377414
2377417
2377418
2377424
2377425
2377426
2377439
2377534
2377545
2377553
2377570
239205_PM_s_at
239205_s_at
244313_PM_at
244313_at
35892_at
35893_s_at
54383_g_at
60374_at
7909371
A_23_P256821
A_24_P265523
GE528090
GE62914
GO:0001618
GO:0001851
GO:0001855
GO:0001861
GO:0001970
GO:0001971
GO:0002376
GO:0002430
GO:0002435
GO:0002456
GO:0002638
GO:0004877
GO:0005515
GO:0005576
GO:0005615
GO:0005856
GO:0005886
GO:0006957
GO:0006958
GO:0007009
GO:0007155
GO:0008284
GO:0009986
GO:0016020
GO:0023052
GO:0030154
GO:0030667
GO:0031410
GO:0032689
GO:0032703
GO:0042130
GO:0043226
GO:0044853
GO:0045087
GO:0045591
GO:0045916
GO:0045957
GO:0045959
GO:0046718
GO:0048856
GO:0060089
GO:0061024
GO:0070062
GO:0098542
GO:0101003
GO:1900004
GO:1900005
GO:1900099
GO:1903660
GO:1904669
HMNXSV003009834
Hs.133255.0.A1_3p_at
Hs.89688.0.A1_3p_s_at
ILMN_1711611
ILMN_1742601
ILMN_1767193
ILMN_2388112
L17418_cds2_s_at
PH_hs_0023850
TC01001738.hg
X05309_at
g10834973_3p_x_at
g10834995_3p_a_at
Participates
as a member of
Ficolin-rich granule membrane proteins [ficolin-1-rich granule membrane] (Homo sapiens)
Other forms of this molecule
CR1 [secretory granule membrane]
CR1 [plasma membrane]
Inferred To
CT26106 [ficolin-1-rich granule membrane]
(Drosophila melanogaster)
Cr1l [ficolin-1-rich granule membrane]
(Rattus norvegicus)
LOC490269 [ficolin-1-rich granule membrane]
(Canis familiaris)
CR1 [ficolin-1-rich granule membrane]
(Gallus gallus)
CR1 [ficolin-1-rich granule membrane]
(Sus scrofa)
Cross References
RefSeq
NP_000642.3
,
NP_000564.2
OpenTargets
ENSG00000203710
GeneCards
P17927
HPA
ENSG00000203710-CR1
Ensembl
ENSP00000356018
,
ENSG00000203710
,
ENST00000367051
,
ENST00000367053
,
ENSP00000356020
,
ENSP00000383744
,
ENST00000400960
PRO
P17927
Pharos - Targets
P17927
PDB
1PPQ
,
2Q7Z
,
2MCY
,
1GKN
,
1GKG
,
5FO9
,
2MCZ
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
IntAct:EBI-12735745 C3B
0.722
3
UniProt:P48740-2 MASP1
0.623
5
UniProt:P11226 MBL2
1
MBL2 [extracellular region]
(R-HSA-166674)
0.623
8
IntAct:EBI-6264901 C1Q
0.558
6
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