Reactome | TP53 binds the TRIAP1 gene

TP53 binds the TRIAP1 gene

Stable Identifier

R-HSA-6801209

Type

Reaction [binding]

Species

Homo sapiens

Compartment

nucleoplasm

ReviewStatus

5/5

Locations in the PathwayBrowser

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Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional Regulation by TP53 (Homo sapiens)
      - TP53 Regulates Transcription of Cell Death Genes (Homo sapiens)
        
        TP53 Regulates Transcription of Genes Involved in Cytochrome C Release (Homo sapiens)
        
        TP53 binds the TRIAP1 gene (Homo sapiens)

General

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TP53 (p53) binds the p53 response element in the second exon of the TRIAP1 (p53CSV) gene (Park and Nakamura 2005).

Literature References

PubMed ID	Title	Journal	Year
15735003	p53CSV, a novel p53-inducible gene involved in the p53-dependent cell-survival pathway Nakamura, Y, Park, WR	Cancer Res.	2005

Participants

Input

Output

p-S15,S20-TP53 Tetramer:TRIAP1 Gene [nucleoplasm] (Homo sapiens)

Participates

as an event of

TP53 Regulates Transcription of Genes Involved in Cytochrome C Release (Homo sapiens)

Authored

Orlic-Milacic, M (2015-10-14)

Reviewed

Zaccara, S (2016-02-04)

Inga, A (2016-02-04)

Created

Orlic-Milacic, M (2015-10-01)

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