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AMPD3 [secretory granule lumen]
Stable Identifier
R-HSA-6801064
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
secretory granule lumen
Synonyms
AMP deaminase isoform E, AMP deaminase 3, erythrocyte AMP deaminase, AMP deaminase 3 (EC 3.5.4.6) (AMP deaminase isoform E) (Erythrocyte AMP deaminase), Erythrocyte AMP deaminase
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of secretory granule lumen proteins (Homo sapiens)
Secretory granule lumen proteins [secretory granule lumen] (Homo sapiens)
AMPD3 [secretory granule lumen] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
618880
Human erythrocyte 5'-AMP aminohydrolase. Purification and characterization.
Suelter, CH
,
Yun, S
J Biol Chem
1978
The Metabolic and Molecular Bases of Inherited Disease, 8th ed
Beaudet, AL
,
Scriver, CR
,
Sly, WS
,
Valle, D
2001
External Reference Information
External Reference
UniProt:Q01432 AMPD3
Gene Names
AMPD3
Chain
chain:1-767
Reference Genes
BioGPS Gene:272 AMPD3
COSMIC (genes):AMPD3 AMPD3
CTD Gene:272 AMPD3
dbSNP Gene:272 AMPD3
ENSEMBL:ENSG00000133805 AMPD3
HGNC:470 AMPD3
KEGG:hsa:272 AMPD3
Monarch:272 AMPD3
NCBI Gene:272 AMPD3
OMIM:102772 AMPD3
UCSC:Q01432 AMPD3
Reference Transcript
RefSeq:NM_000480.2 AMPD3
RefSeq:NM_001025390.1 AMPD3
RefSeq:NM_001025389.1 AMPD3
RefSeq:NM_001172431.1 AMPD3
RefSeq:NM_001172430.1 AMPD3
Other Identifiers
11734064_a_at
11734065_a_at
11739419_a_at
11739420_a_at
11741184_a_at
11749016_a_at
11758009_s_at
16721916
207992_PM_s_at
207992_s_at
209491_PM_s_at
209491_s_at
272
2817836
3320142
3320146
3320163
3320165
3320170
3320171
3320172
3320173
3320179
3320180
3320181
3320182
3320183
3320189
3320195
3320196
3320198
3320199
3320201
3320207
3320208
3320209
3320210
3320211
3320213
3320215
3320217
3320218
3320222
3320226
3320227
3320228
3320229
3320231
3320232
3320233
3320234
3320235
38463_s_at
4037701
7938396
A_14_P115542
A_14_P135756
A_23_P116286
A_24_P304154
A_33_P3216938
D12775_s_at
GE558509
GE60534
GO:0003824
GO:0003876
GO:0005515
GO:0005576
GO:0005829
GO:0006188
GO:0006196
GO:0009117
GO:0009168
GO:0016787
GO:0019239
GO:0032264
GO:0034774
GO:0046033
GO:0046872
GO:0055086
GO:1901135
GO:1904813
HMNXSV003033398
HMNXSV003036987
Hs.195363.0.A1_3p_at
Hs.83918.1.S1_3p_a_at
ILMN_1660854
ILMN_1665307
ILMN_1731223
ILMN_1774447
ILMN_1866549
PH_hs_0004781
TC11000183.hg
TC11000184.hg
TC11002554.hg
g4502078_3p_a_at
Participates
as a member of
Secretory granule lumen proteins [secretory granule lumen] (Homo sapiens)
Other forms of this molecule
AMPD3 [cytosol]
AMPD3 [ficolin-1-rich granule lumen]
AMPD3 [extracellular region]
Inferred To
AMPdeam [secretory granule lumen]
(Drosophila melanogaster)
ampd3 [secretory granule lumen]
(Xenopus tropicalis)
ampd-1 [secretory granule lumen]
(Caenorhabditis elegans)
AMPD3 [secretory granule lumen]
(Bos taurus)
AMPD3 [secretory granule lumen]
(Canis familiaris)
AMPD3 [secretory granule lumen]
(Dictyostelium discoideum)
AMPD3 [secretory granule lumen]
(Gallus gallus)
AMPD3 [secretory granule lumen]
(Mus musculus)
AMPD3 [secretory granule lumen]
(Plasmodium falciparum)
AMPD3 [secretory granule lumen]
(Rattus norvegicus)
AMPD3 [secretory granule lumen]
(Saccharomyces cerevisiae)
AMPD3 [secretory granule lumen]
(Schizosaccharomyces pombe)
AMPD3 [secretory granule lumen]
(Sus scrofa)
ampd3b [secretory granule lumen]
(Danio rerio)
Homologues of AMPD3 [secretory granule lumen]
(Saccharomyces cerevisiae)
Cross References
ENSEMBL
ENSP00000436987
,
ENSP00000379801
,
ENSP00000379802
,
ENST00000444303
,
ENSP00000431648
,
ENSP00000396000
,
ENST00000528723
,
ENST00000396554
,
ENST00000396553
,
ENST00000529507
OpenTargets
ENSG00000133805
HPA
ENSG00000133805-AMPD3
ZINC - Substances
AMPD3_HUMAN
ZINC target
Q01432
PRO
Q01432
Pharos - Targets
Q01432
Orphanet
AMPD3
ZINC - Predictions - Purchasable
AMPD3_HUMAN
HMDB Protein
HMDBP00597
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P08238 HSP90AB1
6
HSP90AB1 [lysosomal lumen]
(R-HSA-9622846)
HSP90AB1 [nucleoplasm]
(R-HSA-5082399)
HSP90AB1 [cytosol]
(R-HSA-419617)
HSP90AB1 [secretory granule lumen]
(R-HSA-6801477)
HSP90AB1 [extracellular region]
(R-HSA-6806463)
HSP90AB1 [ficolin-1-rich granule lumen]
(R-HSA-6801491)
0.499
2
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