Reactome | CD47 [tertiary granule membrane]

CD47 [tertiary granule membrane]

Stable Identifier

R-HSA-6801033

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

tertiary granule membrane

Synonyms

Leukocyte surface antigen CD47, CD47_HUMAN, Integrin-associated protein, IAP

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External Reference Information

External Reference

UniProt:Q08722 CD47

Gene Names

CD47, MER6

Chain

signal peptide:1-18, chain:19-323

Reference Genes

BioGPS Gene:961 CD47

COSMIC (genes):CD47 CD47

CTD Gene:961 CD47

dbSNP Gene:961 CD47

ENSEMBL:ENSG00000196776 CD47

HGNC:1682 CD47

KEGG:hsa:961 CD47

Monarch:961 CD47

NCBI Gene:961 CD47

OMIM:601028 CD47

UCSC:Q08722 CD47

Reference Transcript

Participates

as a member of

Tertiary granule membrane proteins [tertiary granule membrane] (Homo sapiens)

Other forms of this molecule

CD47 [plasma membrane]

CD47 [specific granule membrane]

Inferred To

CD47 [tertiary granule membrane] (Bos taurus)

CD47 [tertiary granule membrane] (Canis familiaris)

CD47 [tertiary granule membrane] (Gallus gallus)

CD47 [tertiary granule membrane] (Sus scrofa)

Cd47 [tertiary granule membrane] (Mus musculus)

Cd47 [tertiary granule membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_942088.1, NP_001768.1

Guide to Pharmacology - Targets

2943

OpenTargets

ENSG00000196776

ENSEMBL

ENST00000355354, ENSG00000196776, ENSP00000347512, ENST00000361309, ENSP00000355361

HPA

ENSG00000196776-CD47

GeneCards

CD47

PRO

Q08722

Pharos - Targets

Q08722

GlyGen

Q08722

PDB

5IWL, 7WN8, 4KJY, 7MYZ, 5TZT, 4CMM, 5TZ2, 2VSC, 5TZU, 7XJF, 2JJT, 2JJS, 8RP8, 7YGG

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P78324 SIRPA	4	SIRPA [plasma membrane] (R-HSA-3209922) SIRPA [tertiary granule membrane] (R-HSA-6803288) SIRPA [ficolin-1-rich granule membrane] (R-HSA-6803321) p-Y429,Y453,Y470,Y496-SIRPA [plasma membrane] (R-HSA-391102)	0.59	2
UniProt:Q8N205 SYNE4			0.556	3
UniProt:O43914 TYROBP	3	p-Y91,Y102-TYROBP [plasma membrane] (R-HSA-210010) TYROBP [plasma membrane] (R-HSA-198087) TYROBP [secretory granule membrane] (R-HSA-6804800)	0.527	2
UniProt:Q9UK22 FBXO2	1	FBXO2 [cytosol] (R-HSA-976044)	0.527	2
UniProt:Q8NHJ6 LILRB4	1	LILRB4 [plasma membrane] (R-HSA-197718)	0.527	3

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