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IMPDH1 [secretory granule lumen]
Stable Identifier
R-HSA-6800971
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
secretory granule lumen
Synonyms
IMP (inosine monophosphate) dehydrogenase 1, Inosine-5'-monophosphate dehydrogenase 1 (EC 1.1.1.205) (IMP dehydrogenase 1) (IMPDH-I) (IMPD 1), Inosine-5'-monophosphate dehydrogenase 1 , IMP dehydrogenase 1, IMPDH-I, IMPD 1
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of secretory granule lumen proteins (Homo sapiens)
Secretory granule lumen proteins [secretory granule lumen] (Homo sapiens)
IMPDH1 [secretory granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P20839 IMPDH1
Gene Names
IMPDH1, IMPD1
Chain
initiator methionine:, chain:2-514
Reference Genes
BioGPS Gene:3614 IMPDH1
COSMIC (genes):IMPDH1 IMPDH1
CTD Gene:3614 IMPDH1
dbSNP Gene:3614 IMPDH1
ENSEMBL:ENSG00000106348 IMPDH1
HGNC:6052 IMPDH1
KEGG:hsa:3614 IMPDH1
Monarch:3614 IMPDH1
NCBI Gene:3614 IMPDH1
OMIM:146690 IMPDH1
UCSC:P20839 IMPDH1
Reference Transcript
RefSeq:NM_001142573.1 IMPDH1
RefSeq:NM_001304521.1 IMPDH1
RefSeq:NM_001142574.1 IMPDH1
RefSeq:NM_000883.3 IMPDH1
RefSeq:NM_183243.2 IMPDH1
RefSeq:NM_001142576.1 IMPDH1
RefSeq:NM_001102605.1 IMPDH1
RefSeq:XM_017012172.1 IMPDH1
RefSeq:NM_001142575.1 IMPDH1
Participates
as a member of
Secretory granule lumen proteins [secretory granule lumen] (Homo sapiens)
Other forms of this molecule
IMPDH1 [ficolin-1-rich granule lumen]
IMPDH1 [extracellular region]
IMPDH1 [azurophil granule lumen]
IMPDH1 [cytosol]
Inferred To
Homologues of IMPDH1 [secretory granule lumen]
(Saccharomyces cerevisiae)
IMPDH1 [secretory granule lumen]
(Bos taurus)
IMPDH1 [secretory granule lumen]
(Caenorhabditis elegans)
IMPDH1 [secretory granule lumen]
(Canis familiaris)
IMPDH1 [secretory granule lumen]
(Danio rerio)
IMPDH1 [secretory granule lumen]
(Dictyostelium discoideum)
IMPDH1 [secretory granule lumen]
(Drosophila melanogaster)
IMPDH1 [secretory granule lumen]
(Mus musculus)
IMPDH1 [secretory granule lumen]
(Plasmodium falciparum)
IMPDH1 [secretory granule lumen]
(Rattus norvegicus)
IMPDH1 [secretory granule lumen]
(Saccharomyces cerevisiae)
IMPDH1 [secretory granule lumen]
(Schizosaccharomyces pombe)
IMPDH1 [secretory granule lumen]
(Sus scrofa)
IMPDH1 [secretory granule lumen]
(Xenopus tropicalis)
Cross References
Guide to Pharmacology - Targets
2624
OpenTargets
ENSG00000106348
ENSEMBL
ENST00000419067
,
ENSP00000346219
,
ENSP00000420185
,
ENSG00000106348
,
ENST00000496200
,
ENST00000348127
,
ENSP00000345096
,
ENST00000480861
,
ENSP00000265385
,
ENSP00000399400
,
ENST00000338791
,
ENSP00000420803
,
ENST00000354269
ZINC - FDA approved
IMDH1_HUMAN
ZINC - Substances
IMDH1_HUMAN
ZINC - Biogenic
IMDH1_HUMAN
ZINC target
P20839
PRO
P20839
GlyGen
P20839
PDB
7RGI
,
7RGM
,
7RER
,
7RGL
,
1JCN
,
7RFE
,
7RGD
,
8U7M
,
7RFF
,
7RES
,
7RGQ
,
7RFI
,
7RFG
,
7RFH
,
8U7Q
,
8U7V
,
8U8Y
,
8U8O
IntEnz
1.1.1.205
HPA
ENSG00000106348-IMPDH1
GeneCards
IMPDH1
Pharos - Targets
P20839
Orphanet
IMPDH1
ZINC - Predictions - Purchasable
IMDH1_HUMAN
HMDB Protein
HMDBP00883
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