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NDUF subunits bind to form the FP subcomplex
Stable Identifier
R-HSA-6800870
Type
Reaction [binding]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
,
mitochondrial matrix
ReviewStatus
5/5
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Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Respiratory electron transport (Homo sapiens)
Complex I biogenesis (Homo sapiens)
NDUF subunits bind to form the FP subcomplex (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Subunits NDUFA12, NDUFS1, 4, 6, NDUFV1, 2 and 3 with the assembly factor NDUFAF2 comprises the peripheral arm, called the flavoprotein (FP) subcomplex (Mimaki et al. 2012).
Literature References
PubMed ID
Title
Journal
Year
21924235
Understanding mitochondrial complex I assembly in health and disease
Wang, X
,
Ryan, MT
,
Thorburn, DR
,
McKenzie, M
,
Mimaki, M
Biochim. Biophys. Acta
2012
Participants
Input
NDUFA12 [mitochondrial inner membrane]
(Homo sapiens)
NDUFAF2 [mitochondrial inner membrane]
(Homo sapiens)
NDUFS1:2x4Fe-4S [mitochondrial matrix]
(Homo sapiens)
NDUFS4 [mitochondrial inner membrane]
(Homo sapiens)
NDUFS6 [mitochondrial inner membrane]
(Homo sapiens)
NDUFV1:4Fe-4S:FMN [mitochondrial inner membrane]
(Homo sapiens)
NDUFV2:4Fe-4S [mitochondrial inner membrane]
(Homo sapiens)
NDUFV3 [mitochondrial inner membrane]
(Homo sapiens)
Output
FP subcomplex [mitochondrial inner membrane]
(Homo sapiens)
Participates
as an event of
Complex I biogenesis (Homo sapiens)
Orthologous Events
NDUF subunits bind to form the FP subcomplex (Bos taurus)
NDUF subunits bind to form the FP subcomplex (Mus musculus)
NDUF subunits bind to form the FP subcomplex (Rattus norvegicus)
Authored
Jassal, B (2015-09-30)
Reviewed
Meldal, BH (2015-10-01)
Created
Jassal, B (2015-09-30)
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