Reactome | KRT1 [extracellular region]

KRT1 [extracellular region]

Stable Identifier

R-HSA-6800471

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Keratin, type II cytoskeletal 1, K2C1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P04264 KRT1

Gene Names

KRT1, KRTA

Chain

initiator methionine:, chain:2-644

Reference Genes

BioGPS Gene:3848 KRT1

COSMIC (genes):KRT1 KRT1

CTD Gene:3848 KRT1

dbSNP Gene:3848 KRT1

ENSEMBL:ENSG00000167768 KRT1

ENSEMBL_homo_sapiens_GENE:ENSG00000167768.4 KRT1

HGNC:6412 KRT1

KEGG Gene (Homo sapiens):3848 KRT1

Monarch:3848 KRT1

NCBI Gene:3848 KRT1

OMIM:139350 KRT1

UCSC:P04264 KRT1

Reference Transcript

RefSeq:NM_006121.3 KRT1

Other Identifiers

11723952_at

16765029

205900_PM_at

205900_at

3455729

3455730

3455731

3455732

3455733

3455734

3455737

3455738

3455740

3455741

3455742

3455743

3455744

3455745

3455746

3455747

3455748

3848

558_at

7963491

A_23_P128235

A_33_P3379396

GE81598

GO:0001533

GO:0001867

GO:0002376

GO:0005198

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005737

GO:0005829

GO:0005856

GO:0005882

GO:0005886

GO:0006954

GO:0006979

GO:0007010

GO:0016020

GO:0018149

GO:0030154

GO:0030246

GO:0030280

GO:0030312

GO:0031012

GO:0031410

GO:0031424

GO:0036211

GO:0038023

GO:0042060

GO:0042730

GO:0043226

GO:0045095

GO:0045109

GO:0045765

GO:0046982

GO:0048856

GO:0050728

GO:0051290

GO:0060089

GO:0061436

GO:0062023

GO:0065003

GO:0070062

GO:0072562

GO:0098542

GO:1904813

HMNXSV003029368

ILMN_1735712

M98776_rna1_at

PH_hs_0004646

TC12001532.hg

Participates

as a member of

Ficolin-rich granule lumen proteins [extracellular region] (Homo sapiens)

Other forms of this molecule

KRT1 [cytosol]

KRT1 [ficolin-1-rich granule lumen]

Inferred To

Homologues of KRT1 [extracellular region] (Danio rerio)

Homologues of KRT1 [extracellular region] (Gallus gallus)

Homologues of KRT1 [extracellular region] (Xenopus tropicalis)

krt61 [extracellular region] (Xenopus tropicalis)

krt5 [extracellular region] (Danio rerio)

krt78.4 [extracellular region] (Xenopus tropicalis)

krt8 [extracellular region] (Danio rerio)

Krt1 [extracellular region] (Mus musculus)

Krt1 [extracellular region] (Rattus norvegicus)

KRT1 [extracellular region] (Bos taurus)

KRT1 [extracellular region] (Gallus gallus)

KRT1 [extracellular region] (Sus scrofa)

krt6b [extracellular region] (Xenopus tropicalis)

wu:fb58f07 [extracellular region] (Danio rerio)

Cross References

RefSeq

NP_006112.3

OpenTargets

ENSG00000167768

GeneCards

P04264

HPA

ENSG00000167768-KRT1

Ensembl

ENST00000252244, ENSG00000167768, ENSP00000252244

PRO

P04264

Pharos - Targets

P04264

Orphanet

16314

PDB

4ZRY, 6E2J, 6UUI

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.718	6
UniProt:P14373 TRIM27	2	TRIM27 [nucleoplasm] (R-HSA-2997690) TRIM27 [cytosol] (R-HSA-8851002)	0.601	4
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.556	3
UniProt:O15552 FFAR2	1	FFAR2 [plasma membrane] (R-HSA-443944)	0.556	3
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4