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PRSS3 [tertiary granule lumen]
Stable Identifier
R-HSA-6800432
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
tertiary granule lumen
Synonyms
Trypsin-3, TRY3_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Developmental Cell Lineages (Homo sapiens)
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin (Homo sapiens)
Keratinocyte of granulosum layer differentiates into corneocyte of corneum layer in interfollicular epidermis (Homo sapiens)
keratinocyte of granulosum layer of epidermis (Homo sapiens)
PRSS3 [tertiary granule lumen] (Homo sapiens)
Keratinocyte of spinosum layer differentiates into keratinocyte of granulosum layer in interfollicular epidermis (Homo sapiens)
keratinocyte of granulosum layer of epidermis (Homo sapiens)
PRSS3 [tertiary granule lumen] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of tertiary granule lumen proteins (Homo sapiens)
Tertiary granule lumen proteins [tertiary granule lumen] (Homo sapiens)
PRSS3 [tertiary granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P35030 PRSS3
Gene Names
PRSS3, PRSS4, TRY3, TRY4
Chain
signal peptide:1-, propeptide:-80, chain:81-304
Reference Genes
BioGPS Gene:5646 PRSS3
COSMIC (genes):PRSS3 PRSS3
CTD Gene:5646 PRSS3
dbSNP Gene:5646 PRSS3
ENSEMBL:ENSG00000010438 PRSS3
HGNC:9486 PRSS3
KEGG:hsa:5646 PRSS3
Monarch:5646 PRSS3
NCBI Gene:5646 PRSS3
OMIM:613578 PRSS3
UCSC:P35030 PRSS3
Reference Transcript
RefSeq:NM_001197097.2 PRSS3
RefSeq:NM_007343.3 PRSS3
RefSeq:NM_001197098.1 PRSS3
RefSeq:NM_002771.3 PRSS3
Other Identifiers
11719384_at
11751745_x_at
17084389
207463_PM_x_at
207463_x_at
213421_PM_x_at
213421_x_at
3028746
3028762
3028764
3028765
3028781
3028782
3028789
3028795
3028805
3028807
3028811
3028815
3028827
3028843
3167188
3167191
3167202
3167203
3167204
3167205
3167207
3167208
3167211
3167212
3167213
3167214
3167215
3167216
3167217
32796_f_at
3356039
40043_at
5646
60083_at
8154848
A_23_P135257
GE81191
GO:0002376
GO:0003824
GO:0004252
GO:0005509
GO:0005515
GO:0005576
GO:0005615
GO:0006508
GO:0007586
GO:0008236
GO:0016787
GO:0019730
GO:0031638
GO:0043542
GO:0046872
GO:0048870
GO:0051604
GO:0098542
GO:0140096
GO:1904724
HMNXSV003028248
Hs.303157.10.S1_3p_x_at
Hs.58247.0.A1_3p_s_at
ILMN_1685699
PH_hs_0033374
TC09000155.hg
X71345_f_at
Participates
as a protein marker of
keratinocyte of granulosum layer of epidermis (Homo sapiens)
as a member of
Tertiary granule lumen proteins [tertiary granule lumen] (Homo sapiens)
Other forms of this molecule
PRSS3 [extracellular region]
Inferred To
Prss3 [tertiary granule lumen]
(Mus musculus)
Prss3 [tertiary granule lumen]
(Rattus norvegicus)
Homologues of PRSS3 [tertiary granule lumen]
(Danio rerio)
Homologues of PRSS3 [tertiary granule lumen]
(Gallus gallus)
Homologues of PRSS3 [tertiary granule lumen]
(Mus musculus)
Homologues of PRSS3 [tertiary granule lumen]
(Rattus norvegicus)
Homologues of PRSS3 [tertiary granule lumen]
(Xenopus tropicalis)
Prss3l [tertiary granule lumen]
(Mus musculus)
try10 [tertiary granule lumen]
(Xenopus tropicalis)
tpsb2 [tertiary granule lumen]
(Xenopus tropicalis)
try [tertiary granule lumen]
(Sus scrofa)
Prss2l1 [tertiary granule lumen]
(Rattus norvegicus)
LOC101730988 [tertiary granule lumen]
(Xenopus tropicalis)
LOC116412104 [tertiary granule lumen]
(Xenopus tropicalis)
PRSS2 [tertiary granule lumen]
(Bos taurus)
PRSS2 [tertiary granule lumen]
(Canis familiaris)
LOC102554637 [tertiary granule lumen]
(Rattus norvegicus)
PRSS3 [tertiary granule lumen]
(Mus musculus)
PRSS3 [tertiary granule lumen]
(Rattus norvegicus)
LOC101732100 [tertiary granule lumen]
(Xenopus tropicalis)
si:dkey-33m11.8 [tertiary granule lumen]
(Danio rerio)
Try5 [tertiary granule lumen]
(Mus musculus)
Try5 [tertiary granule lumen]
(Rattus norvegicus)
Prss1l [tertiary granule lumen]
(Mus musculus)
wu:fd14c02 [tertiary granule lumen]
(Danio rerio)
LOC100485189 [tertiary granule lumen]
(Xenopus tropicalis)
LOC107054567 [tertiary granule lumen]
(Gallus gallus)
prss59.2 [tertiary granule lumen]
(Danio rerio)
Prss1 [tertiary granule lumen]
(Mus musculus)
Try10 [tertiary granule lumen]
(Mus musculus)
Try10 [tertiary granule lumen]
(Rattus norvegicus)
LOC105945797 [tertiary granule lumen]
(Xenopus tropicalis)
LOC121107389 [tertiary granule lumen]
(Gallus gallus)
prss59.1 [tertiary granule lumen]
(Danio rerio)
prss1 [tertiary granule lumen]
(Danio rerio)
Cross References
RefSeq
NP_001184026.2
,
NP_001184027.1
,
NP_031369.2
,
NP_002762.2
Guide to Pharmacology - Targets
2399
OpenTargets
ENSG00000010438
ENSEMBL
ENSP00000401828
,
ENST00000429677
,
ENST00000379405
,
ENSP00000368715
,
ENSG00000010438
ZINC - Substances
TRY3_HUMAN
ZINC target
P35030
PRO
P35030
GlyGen
P35030
PDB
5TP0
,
1H4W
,
4DG4
,
4U32
,
4U30
,
6BX8
,
5JBT
,
3P95
,
6GFI
,
3L3T
,
3P92
,
2R9P
,
3L33
,
5C67
HPA
ENSG00000010438-PRSS3
GeneCards
PRSS3
Pharos - Targets
P35030
ZINC - Predictions - Purchasable
TRY3_HUMAN
HMDB Protein
HMDBP08088
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