Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
PRSS3 [tertiary granule lumen]
Stable Identifier
R-HSA-6800432
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
tertiary granule lumen
Synonyms
Trypsin-3, TRY3_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Developmental Cell Lineages (Homo sapiens)
Differentiation of keratinocytes in interfollicular epidermis in mammalian skin (Homo sapiens)
Keratinocyte of granulosum layer differentiates into corneocyte of corneum layer in interfollicular epidermis (Homo sapiens)
keratinocyte of granulosum layer of epidermis (Homo sapiens)
PRSS3 [tertiary granule lumen] (Homo sapiens)
Keratinocyte of spinosum layer differentiates into keratinocyte of granulosum layer in interfollicular epidermis (Homo sapiens)
keratinocyte of granulosum layer of epidermis (Homo sapiens)
PRSS3 [tertiary granule lumen] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of tertiary granule lumen proteins (Homo sapiens)
Tertiary granule lumen proteins [tertiary granule lumen] (Homo sapiens)
PRSS3 [tertiary granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P35030 PRSS3
Gene Names
PRSS3, PRSS4, TRY3, TRY4
Chain
signal peptide:1-, propeptide:-80, chain:81-304
Reference Genes
BioGPS Gene:5646 PRSS3
COSMIC (genes):PRSS3 PRSS3
CTD Gene:5646 PRSS3
dbSNP Gene:5646 PRSS3
ENSEMBL:ENSG00000010438 PRSS3
ENSEMBL_homo_sapiens_GENE:ENSG00000010438.17 PRSS3
HGNC:9486 PRSS3
KEGG Gene (Homo sapiens):5646 PRSS3
Monarch:5646 PRSS3
NCBI Gene:5646 PRSS3
OMIM:613578 PRSS3
UCSC:P35030 PRSS3
Reference Transcript
RefSeq:NM_001197098.1 PRSS3
RefSeq:NM_001197097.2 PRSS3
RefSeq:NM_002771.3 PRSS3
RefSeq:NM_007343.3 PRSS3
Other Identifiers
11751745_x_at
207463_PM_x_at
207463_x_at
213421_PM_x_at
213421_x_at
3028762
3028764
3028765
3028782
3028789
3028795
3028805
3028807
3028811
3028815
3028827
3028843
3167205
3167207
3167208
3167211
3167213
3167214
3167215
3167216
3167217
32796_f_at
40043_at
5646
60083_at
8154848
A_23_P135257
GE81191
GO:0002376
GO:0003824
GO:0004252
GO:0005509
GO:0005515
GO:0005576
GO:0005615
GO:0006508
GO:0007586
GO:0008233
GO:0008236
GO:0016787
GO:0019730
GO:0031410
GO:0031638
GO:0043226
GO:0043542
GO:0046872
GO:0048870
GO:0051604
GO:0098542
GO:0140096
GO:1904724
HMNXSV003028248
Hs.303157.10.S1_3p_x_at
PH_hs_0033374
X71345_f_at
Participates
as a protein marker of
keratinocyte of granulosum layer of epidermis (Homo sapiens)
as a member of
Tertiary granule lumen proteins [tertiary granule lumen] (Homo sapiens)
Other forms of this molecule
PRSS3 [extracellular region]
Inferred To
LOC102554637 [tertiary granule lumen]
(Rattus norvegicus)
Prss3 [tertiary granule lumen]
(Mus musculus)
Prss3 [tertiary granule lumen]
(Rattus norvegicus)
PRSS3 [tertiary granule lumen]
(Danio rerio)
PRSS3 [tertiary granule lumen]
(Mus musculus)
PRSS3 [tertiary granule lumen]
(Rattus norvegicus)
Homologues of PRSS3 [tertiary granule lumen]
(Danio rerio)
Homologues of PRSS3 [tertiary granule lumen]
(Gallus gallus)
Homologues of PRSS3 [tertiary granule lumen]
(Mus musculus)
Homologues of PRSS3 [tertiary granule lumen]
(Rattus norvegicus)
Homologues of PRSS3 [tertiary granule lumen]
(Xenopus tropicalis)
LOC101732100 [tertiary granule lumen]
(Xenopus tropicalis)
Try5 [tertiary granule lumen]
(Mus musculus)
Try5 [tertiary granule lumen]
(Rattus norvegicus)
Prss1l [tertiary granule lumen]
(Mus musculus)
Prss3l [tertiary granule lumen]
(Mus musculus)
try10 [tertiary granule lumen]
(Xenopus tropicalis)
wu:fd14c02 [tertiary granule lumen]
(Danio rerio)
LOC100485189 [tertiary granule lumen]
(Xenopus tropicalis)
tpsb2 [tertiary granule lumen]
(Xenopus tropicalis)
LOC107054567 [tertiary granule lumen]
(Gallus gallus)
prss2a [tertiary granule lumen]
(Danio rerio)
try [tertiary granule lumen]
(Danio rerio)
try [tertiary granule lumen]
(Sus scrofa)
si:ch73-103b2.3 [tertiary granule lumen]
(Danio rerio)
Prss1 [tertiary granule lumen]
(Mus musculus)
Try10 [tertiary granule lumen]
(Mus musculus)
Try10 [tertiary granule lumen]
(Rattus norvegicus)
LOC101730988 [tertiary granule lumen]
(Xenopus tropicalis)
LOC116412104 [tertiary granule lumen]
(Xenopus tropicalis)
LOC683849 [tertiary granule lumen]
(Rattus norvegicus)
PRSS2 [tertiary granule lumen]
(Bos taurus)
PRSS2 [tertiary granule lumen]
(Canis familiaris)
LOC105945797 [tertiary granule lumen]
(Xenopus tropicalis)
LOC121107389 [tertiary granule lumen]
(Gallus gallus)
Cross References
RefSeq
NP_031369.2
,
NP_001184027.1
,
NP_001184026.2
,
NP_002762.2
Guide to Pharmacology - Targets
2399
OpenTargets
ENSG00000010438
ZINC - Substances
TRY3_HUMAN
ZINC target
P35030
PRO
P35030
PDB
5C67
,
2R9P
,
5JBT
,
4DG4
,
5TP0
,
3L33
,
6BX8
,
3P92
,
4U32
,
3L3T
,
4U30
,
1H4W
,
6GFI
,
3P95
GeneCards
P35030
HPA
ENSG00000010438-PRSS3
Ensembl
ENSP00000368715
,
ENST00000429677
,
ENST00000379405
,
ENSP00000401828
,
ENSG00000010438
Pharos - Targets
P35030
ZINC - Predictions - Purchasable
TRY3_HUMAN
HMDB Protein
HMDBP08088
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text