TP53 binds the BCL6 gene

Stable Identifier
R-HSA-6800253
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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TP53 binds the BCL6 gene
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TP53 (p53) binds the p53 response element located in the first intron of the BCL6 gene. This region of the BCL6 gene is frequently subject to translocations, point mutations and deletions in B-cell non-Hodgkin lymphoma (Margalit et al. 2006).

Literature References
PubMed ID Title Journal Year
16249378 BCL6 is regulated by p53 through a response element frequently disrupted in B-cell non-Hodgkin lymphoma

Shohat, M, Shaklai, S, Amariglio, N, Margalit, O, Granot, G, Givol, D, Minsky, N, Harmelin, A, Simon, AJ, Amram, H, Rechavi, G, Shimoni, A, Oren, M

Blood 2006
Participants
Input
Output
Participates
as an event of
Authored
Orlic-Milacic, M  (2015-10-14)
Reviewed
Zaccara, S  (2016-02-04)
Inga, A  (2016-02-04)
Created
Orlic-Milacic, M  (2015-09-28)
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