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SPINT1,2 [extracellular region]
Stable Identifier
R-HSA-6800235
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by MET (Homo sapiens)
MET Receptor Activation (Homo sapiens)
HPN heterodimer cleaves pro-HGF to form HGF dimer (Homo sapiens)
SPINT1,2 [extracellular region] (Homo sapiens)
Signaling by MST1 (Homo sapiens)
HPN heterodimer cleaves pro-MST1 to form MST1 dimer (Homo sapiens)
SPINT1,2 [extracellular region] (Homo sapiens)
Participants
members
SPINT1 [extracellular region]
(Homo sapiens)
SPINT2 [extracellular region]
(Homo sapiens)
This entity regulates
Negatively
HPN heterodimer cleaves pro-MST1 to form MST1 dimer
(Homo sapiens)
HPN heterodimer cleaves pro-HGF to form HGF dimer
(Homo sapiens)
Inferred To
SPINT1,2 [extracellular region]
(Bos taurus)
SPINT1,2 [extracellular region]
(Canis familiaris)
SPINT1,2 [extracellular region]
(Mus musculus)
SPINT1,2 [extracellular region]
(Rattus norvegicus)
SPINT1,2 [extracellular region]
(Sus scrofa)
spint2 [extracellular region]
(Xenopus tropicalis)
spint1b [extracellular region]
(Danio rerio)
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