The p53 family members TP53 (p53), TP63 (p63), or TP73 (p73), most likely in complex with ASPP proteins PPP1R13B (ASPP1) or TP53BP2 (ASPP2) (Wilson et al. 2013), bind p53 response elements in the first intron and/or promoter of the FAS gene, promoting FAS transcription (Schilling et al. 2009).
Schilling, T, Schleithoff, ES, Kairat, A, Melino, G, Stremmel, W, Oren, M, Krammer, PH, Müller, M
Wilson, AM, Morquette, B, Abdouh, M, Unsain, N, Barker, PA, Feinstein, E, Bernier, G, Di Polo, A
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