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TMC6 [specific granule membrane]
Stable Identifier
R-HSA-6799712
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
specific granule membrane
Synonyms
Transmembrane channel-like protein 6, TMC6_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of specific granule membrane proteins (Homo sapiens)
Specific granule membrane proteins [specific granule membrane] (Homo sapiens)
TMC6 [specific granule membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q7Z403 TMC6
Gene Names
TMC6, EVER1, EVIN1
Chain
chain:1-805
Reference Genes
BioGPS Gene:11322 TMC6
COSMIC (genes):TMC6 TMC6
CTD Gene:11322 TMC6
dbSNP Gene:11322 TMC6
ENSEMBL:ENSG00000141524 TMC6
HGNC:18021 TMC6
KEGG:hsa:11322 TMC6
Monarch:11322 TMC6
NCBI Gene:11322 TMC6
OMIM:605828 TMC6
UCSC:Q7Z403 TMC6
Reference Transcript
RefSeq:XM_005256995.1 TMC6
RefSeq:NM_007267.7 TMC6
RefSeq:NM_001321185.1 TMC6
RefSeq:NM_001127198.2 TMC6
RefSeq:XM_011524255.1 TMC6
Other Identifiers
11322
11719431_a_at
11752637_a_at
11752638_x_at
11761269_x_at
11761568_at
11761569_x_at
11761798_a_at
11761799_x_at
16849349
16849355
204328_PM_at
204328_at
214958_3p_s_at
214958_PM_s_at
214958_s_at
228591_PM_at
228591_at
230526_PM_at
230526_at
239062_PM_at
239062_at
2409184
242364_PM_x_at
242364_x_at
32116_at
3772086
3772088
3772089
3772091
3772092
3772093
3772094
3772095
3772096
3772097
3772098
3772099
3772100
3772101
3772102
3772103
3772104
3772105
3772106
3772107
3772108
3772109
3772110
3772111
3772112
3772113
3772114
3772115
3772116
3772117
3772118
3772119
3772120
3772121
3772122
3772123
3772124
3772125
3772126
3772127
3772128
3772129
3772130
3772131
3772132
3772133
3772134
3772135
3772136
3772137
3772138
3772141
3772142
3772143
3772145
54483_at
57763_at
8018823
89316_at
91502_at
A_23_P101013
A_24_P152743
A_24_P857624
A_32_P19000
GE53101
GE84262
GE86244
GO:0005215
GO:0005515
GO:0005737
GO:0005783
GO:0005789
GO:0005794
GO:0005886
GO:0006882
GO:0008150
GO:0008381
GO:0016020
GO:0031965
GO:0034220
GO:0035579
GO:0043226
GO:0050821
GO:0055085
GO:0070062
GO:0070821
HMNXSV003017549
HMNXSV003026577
Hs.182562.0.A1_3p_at
Hs.182562.1.A1_3p_a_at
Hs.62529.0.A1_3p_at
Hs.80618.1.A1_3p_at
ILMN_1794677
PH_hs_0027086
TC17001912.hg
TC17001913.hg
TC17002799.hg
g7305226_3p_at
p29179
p7064
Participates
as a member of
Specific granule membrane proteins [specific granule membrane] (Homo sapiens)
Other forms of this molecule
TMC6 [plasma membrane]
TMC6 [tertiary granule membrane]
Inferred To
TMC6 [specific granule membrane]
(Bos taurus)
TMC6 [specific granule membrane]
(Canis familiaris)
TMC6 [specific granule membrane]
(Gallus gallus)
TMC6 [specific granule membrane]
(Sus scrofa)
Tmc6 [specific granule membrane]
(Mus musculus)
Tmc6 [specific granule membrane]
(Rattus norvegicus)
tmc6 [specific granule membrane]
(Xenopus tropicalis)
Cross References
ENSEMBL
ENSP00000313408
,
ENSP00000376260
,
ENSP00000466885
,
ENSP00000306405
,
ENST00000589271
,
ENST00000592063
,
ENSG00000141524
,
ENST00000392467
,
ENST00000322914
,
ENSP00000468255
,
ENSP00000465261
,
ENST00000590602
,
ENSP00000513793
,
ENST00000306591
,
ENST00000698550
OpenTargets
ENSG00000141524
GeneCards
TMC6
HPA
ENSG00000141524-TMC6
PRO
Q7Z403
Pharos - Targets
Q7Z403
GlyGen
Q7Z403
Orphanet
TMC6
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P16284 PECAM1
5
PECAM1 [plasma membrane]
(R-HSA-114686)
PECAM1 [secretory granule membrane]
(R-HSA-6804778)
p-Y663,Y686-PECAM1(27-?) [plasma membrane]
(R-HSA-210007)
p-Y713-PECAM1 [plasma membrane]
(R-HSA-9860772)
PECAM1 [platelet alpha granule membrane]
(R-HSA-61489)
0.556
3
UniProt:P08670 VIM
11
Vimentin [lysosomal lumen]
(R-HSA-9659977)
Vimentin [cytosol]
(R-HSA-9646687)
Vimentin [microtubule organizing center]
(R-HSA-9657898)
Vimentin [late endosome lumen]
(R-HSA-9660019)
VIM [cytosol]
(R-HSA-201600)
VIM(2-259) [cytosol]
(R-HSA-350323)
VIM(260-466) [cytosol]
(R-HSA-350314)
VIM(2-429) [cytosol]
(R-HSA-350317)
VIM(430-466) [cytosol]
(R-HSA-350316)
VIM(86-466) [cytosol]
(R-HSA-350294)
VIM(2-85) [cytosol]
(R-HSA-350264)
0.556
3
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