Reactome | GPX5 [extracellular region]

GPX5 [extracellular region]

Stable Identifier

R-HSA-6799693

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Epididymal secretory glutathione peroxidase ecNumber1.11.1.9/ecNumber, GPX5_HUMAN

Locations in the PathwayBrowser

Expand all

Cellular responses to stimuli (Homo sapiens)

- Cellular responses to stress (Homo sapiens)
  - Cellular response to chemical stress (Homo sapiens)
    - Detoxification of Reactive Oxygen Species (Homo sapiens)
      - GPX5,6 reduce H2O2 to H2O (Homo sapiens)
        
        GPX5, (GPX6) [extracellular region] (Homo sapiens)
        
        GPX5 [extracellular region] (Homo sapiens)

External Reference Information

External Reference

UniProt:O75715 GPX5

Gene Names

GPX5

Chain

signal peptide:1-21, chain:22-221

Reference Genes

BioGPS Gene:2880 GPX5

COSMIC (genes):GPX5 GPX5

CTD Gene:2880 GPX5

dbSNP Gene:2880 GPX5

ENSEMBL:ENSG00000224586 GPX5

HGNC:4557 GPX5

KEGG:hsa:2880 GPX5

Monarch:2880 GPX5

NCBI Gene:2880 GPX5

OMIM:603435 GPX5

UCSC:O75715 GPX5

Reference Transcript

Other Identifiers

11738665_a_at

11755714_a_at

17005973

17027203

208028_PM_s_at

208028_s_at

214648_PM_at

214648_at

2880

2900555

2900556

2900561

2900563

2900564

2900565

2900566

2900567

2900568

2900569

2900570

2900571

2900572

2900573

2900574

2900575

2900576

8117700

A_23_P214544

GE80647

GO:0003824

GO:0004601

GO:0004602

GO:0005576

GO:0006629

GO:0006979

GO:0016209

GO:0016491

GO:0034599

GO:0098754

GO:0098869

HMNXSV003018121

Hs.248129.1.S2_3p_at

ILMN_1775871

ILMN_2385410

ILMN_2385416

PH_hs_0029505

TC06000286.hg

TC6_cox_hap2000001.hg

g6715601_3p_a_at

Participates

as a member of

GPX5, (GPX6) [extracellular region] (Homo sapiens)

Inferred To

Homologues of GPX5 [extracellular region] (Bos taurus)

gpx-5 [extracellular region] (Caenorhabditis elegans)

gpx9 [extracellular region] (Danio rerio)

GPX5 [extracellular region] (Bos taurus)

GPX5 [extracellular region] (Canis familiaris)

GPX5 [extracellular region] (Sus scrofa)

Gpx5 [extracellular region] (Mus musculus)

Gpx5 [extracellular region] (Rattus norvegicus)

Cross References

ENSEMBL

ENST00000550775, ENSP00000392398, ENST00000412168, ENSP00000449271, ENSP00000450365, ENST00000551639, ENSG00000257770, ENSG00000224586, ENSP00000419935, ENST00000469384

OpenTargets

ENSG00000224586

GeneCards

GPX5

HPA

ENSG00000224586-GPX5

PRO

O75715

Pharos - Targets

O75715

HMDB Protein

HMDBP00810

PDB

2I3Y

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