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MMP8 [specific granule lumen]
Stable Identifier
R-HSA-6799650
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
specific granule lumen
Synonyms
Neutrophil collagenase, MMP8_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of specific granule lumen proteins (Homo sapiens)
Specific granule lumen proteins [specific granule lumen] (Homo sapiens)
MMP8 [specific granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P22894 MMP8
Gene Names
MMP8, CLG1
Chain
signal peptide:1-20, propeptide:21-100, chain:101-467
Reference Genes
BioGPS Gene:4317 MMP8
COSMIC (genes):MMP8 MMP8
CTD Gene:4317 MMP8
dbSNP Gene:4317 MMP8
ENSEMBL:ENSG00000118113 MMP8
ENSEMBL:ENSG00000118113.12 MMP8
HGNC:7175 MMP8
KEGG Gene (Homo sapiens):4317 MMP8
Monarch:4317 MMP8
NCBI Gene:4317 MMP8
OMIM:120355 MMP8
UCSC:P22894 MMP8
Reference Transcript
RefSeq:NM_001304442.1 MMP8
RefSeq:NM_001304441.1 MMP8
RefSeq:NM_002424.2 MMP8
Other Identifiers
11729349_at
11729350_a_at
11729351_a_at
11748210_a_at
16743686
207329_PM_at
207329_at
231688_PM_at
231688_at
3388749
3388750
3388752
3388753
3388754
3388755
3388756
3388757
3388758
3388759
3388760
3388761
3388762
3388769
3388770
4317
681_at
7951246
A_23_P24493
GE477524
GE57532
GO:0002376
GO:0003824
GO:0004175
GO:0004222
GO:0004252
GO:0005576
GO:0005615
GO:0006508
GO:0006954
GO:0008233
GO:0008237
GO:0008270
GO:0010628
GO:0010629
GO:0016787
GO:0022617
GO:0023052
GO:0030154
GO:0030198
GO:0030312
GO:0030574
GO:0031012
GO:0031410
GO:0032693
GO:0032755
GO:0032760
GO:0035580
GO:0035987
GO:0043226
GO:0043388
GO:0043410
GO:0045429
GO:0046330
GO:0046872
GO:0048856
GO:0062023
GO:0140096
GO:0150077
GO:0150078
GO:1901224
GO:1903428
GO:1903978
GO:1903980
GO:1904724
HMNXSV003012409
Hs.255877.0.A1_3p_at
ILMN_1736026
J05556_at
PH_hs_0024515
TC11002231.hg
g4505220_3p_at
Participates
as a member of
Specific granule lumen proteins [specific granule lumen] (Homo sapiens)
Other forms of this molecule
MMP8(21-467) [extracellular region]
MMP8 [tertiary granule lumen]
MMP8 [extracellular region]
Inferred To
MMP8 [specific granule lumen]
(Bos taurus)
MMP8 [specific granule lumen]
(Caenorhabditis elegans)
MMP8 [specific granule lumen]
(Canis familiaris)
MMP8 [specific granule lumen]
(Drosophila melanogaster)
MMP8 [specific granule lumen]
(Gallus gallus)
MMP8 [specific granule lumen]
(Mus musculus)
MMP8 [specific granule lumen]
(Rattus norvegicus)
MMP8 [specific granule lumen]
(Sus scrofa)
MMP8 [specific granule lumen]
(Xenopus tropicalis)
Homologues of MMP8 [specific granule lumen]
(Caenorhabditis elegans)
Homologues of MMP8 [specific granule lumen]
(Drosophila melanogaster)
Cross References
RefSeq
NP_002415.1
,
NP_001291370.1
,
NP_001291371.1
ZINC - World Drugs
MMP8_HUMAN
Guide to Pharmacology - Targets
1632
OpenTargets
ENSG00000118113
ZINC - Substances
MMP8_HUMAN
ZINC - Biogenic
MMP8_HUMAN
ZINC target
P22894
PRO
P22894
PDB
3DPE
,
3DPF
,
1JH1
,
1JAQ
,
4QKZ
,
1ZS0
,
3DNG
,
1I76
,
1A85
,
1ZVX
,
5H8X
,
1JJ9
,
1I73
,
3TT4
,
1BZS
,
1KBC
,
1ZP5
,
1JAN
,
2OY4
,
2OY2
,
1A86
,
1MNC
,
1JAP
,
1MMB
,
1JAO
ZINC - Investigational
MMP8_HUMAN
ZINC - Metabolites
MMP8_HUMAN
IntEnz
3.4.24.34
HPA
ENSG00000118113-MMP8
GeneCards
P22894
Ensembl
ENSG00000118113
,
ENST00000236826
,
ENSP00000236826
Pharos - Targets
P22894
ZINC - Predictions - Purchasable
MMP8_HUMAN
HMDB Protein
HMDBP07814
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