TP53I3 dimerizes

Stable Identifier
R-HSA-6799466
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
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TP53I3 dimerizes
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TP53I3 (PIG3) forms a homodimer. The dimer interface is formed by two beta strands and an alpha helix of the cofactor-binding domain. Beta strands of the two monomeric subunits are bonded through anti-parallel hydrogen bonds (Porte et al. 2009).

Literature References
PubMed ID Title Journal Year
19349281 Three-dimensional structure and enzymatic function of proapoptotic human p53-inducible quinone oxidoreductase PIG3

Porté, S, Valencia, E, Yakovtseva, EA, Borràs, E, Shafqat, N, Debreczeny, JE, Pike, AC, Oppermann, U, Farrés, J, Fita, I, Parés, X

J. Biol. Chem. 2009
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Orthologous Events
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TP53I3 dimerizes (Gallus gallus)
TP53I3 dimerizes (Sus scrofa)
TP53I3 dimerizes (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2015-10-14)
Reviewed
Zaccara, S  (2016-02-04)
Inga, A  (2016-02-04)
Created
Orlic-Milacic, M  (2015-09-25)