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GDI2 [azurophil granule lumen]
Stable Identifier
R-HSA-6799337
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
azurophil granule lumen
Synonyms
GDI2/Rab GDI beta
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of azurophil granule lumen proteins (Homo sapiens)
Azurophil granule lumen proteins [azurophil granule lumen] (Homo sapiens)
GDI2 [azurophil granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P50395 GDI2
Gene Names
GDI2, RABGDIB
Chain
chain:1-445
Reference Genes
BioGPS Gene:2665 GDI2
COSMIC (genes):GDI2 GDI2
CTD Gene:2665 GDI2
dbSNP Gene:2665 GDI2
ENSEMBL:ENSG00000057608 GDI2
ENSEMBL_homo_sapiens_GENE:ENSG00000057608.17 GDI2
HGNC:4227 GDI2
KEGG Gene (Homo sapiens):2665 GDI2
Monarch:2665 GDI2
NCBI Gene:2665 GDI2
OMIM:600767 GDI2
UCSC:P50395 GDI2
Reference Transcript
RefSeq:NM_001115156.1 GDI2
RefSeq:NM_001494.3 GDI2
Other Identifiers
11736003_x_at
11740677_a_at
11757439_s_at
16711442
18670733
18670734
18670735
18670736
18670738
18670739
18670741
18670742
18670743
18670744
18670745
18670746
18670747
18670748
18670750
18670751
200008_PM_s_at
200008_s_at
200009_PM_at
200009_at
2341978
2665
3275138
3275140
3275141
3275142
3275143
3275145
3275147
3275150
3275151
3275154
3275165
3275166
3275168
3275173
3275174
3275175
3275180
3275181
35307_at
777_at
7892574
7892630
7893732
7894252
7894304
7894395
7894826
7895161
7895263
7895271
7895691
7895985
7896321
7896531
7931873
A_23_P161446
D13988_at
GE60306
GE79890
GO:0003723
GO:0005092
GO:0005093
GO:0005096
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005764
GO:0005773
GO:0005794
GO:0005829
GO:0005925
GO:0007165
GO:0007264
GO:0015031
GO:0016020
GO:0016192
GO:0023052
GO:0031267
GO:0031410
GO:0031982
GO:0034774
GO:0035578
GO:0043226
GO:0044782
GO:0045202
GO:0070062
GO:0098772
GO:1902018
GO:1903565
HMNXSV003014995
ILMN_1754178
PH_hs_0028919
TC10001002.hg
g285974_3p_a_at
g6598322_3p_s_at
Participates
as a member of
Azurophil granule lumen proteins [azurophil granule lumen] (Homo sapiens)
Other forms of this molecule
GDI2 [cytosol]
GDI2 [extracellular region]
GDI2 [secretory granule lumen]
Inferred To
Gdi [azurophil granule lumen]
(Drosophila melanogaster)
gdi-1 [azurophil granule lumen]
(Caenorhabditis elegans)
wu:fc09e02 [azurophil granule lumen]
(Danio rerio)
gdi2 [azurophil granule lumen]
(Xenopus tropicalis)
GDI2 [azurophil granule lumen]
(Bos taurus)
GDI2 [azurophil granule lumen]
(Canis familiaris)
GDI2 [azurophil granule lumen]
(Dictyostelium discoideum)
GDI2 [azurophil granule lumen]
(Gallus gallus)
GDI2 [azurophil granule lumen]
(Plasmodium falciparum)
GDI2 [azurophil granule lumen]
(Sus scrofa)
gdi1 [azurophil granule lumen]
(Schizosaccharomyces pombe)
GDI1 [azurophil granule lumen]
(Saccharomyces cerevisiae)
Homologues of GDI2 [azurophil granule lumen]
(Bos taurus)
Gdi2 [azurophil granule lumen]
(Mus musculus)
Gdi2 [azurophil granule lumen]
(Rattus norvegicus)
Cross References
RefSeq
NP_001485.2
,
NP_001108628.1
OpenTargets
ENSG00000057608
GeneCards
P50395
HPA
ENSG00000057608-GDI2
Ensembl
ENSG00000057608
,
ENST00000380191
,
ENST00000380181
,
ENSP00000369528
,
ENSP00000369538
PRO
P50395
Pharos - Targets
P50395
HMDB Protein
HMDBP01785
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P20339 RAB5A
7
GGC-RAB5A [clathrin-coated endocytic vesicle membrane]
(R-HSA-8871125)
GGC-RAB5A [early endosome membrane]
(R-HSA-8875323)
GGC-RAB5A [cytosol]
(R-HSA-8870432)
RAB5A [cytosol]
(R-HSA-2201187)
GGC-RAB5A [macropinosome membrane]
(R-HSA-9837697)
RAB5A [endosome membrane]
(R-HSA-452257)
RAB5A [early endosome membrane]
(R-HSA-2130175)
0.527
3
UniProt:Q8BMD2
1
Dzip1 [nucleoplasm]
(R-MMU-5635020)
0.499
2
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
7
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