CHEK1, activated by ATR-mediated phosphorylation, can phosphorylate TP53 at serine residue S20, resulting in the increased half-life of TP53 (Shieh et al. 2000).
Tamai, K, Taya, Y, Ahn, J, Prives, C, Shieh, SY
protein serine/threonine kinase activity of p-S317,S345-CHEK1 [nucleoplasm]
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