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MPO (279-745) [azurophil granule lumen]
Stable Identifier
R-HSA-6799241
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
azurophil granule lumen
Synonyms
Myeloperoxidase heavy chain, Myeloperoxidase
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of azurophil granule lumen proteins (Homo sapiens)
Azurophil granule lumen proteins [azurophil granule lumen] (Homo sapiens)
MPO (279-745) [azurophil granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P05164 MPO
Gene Names
MPO
Chain
signal peptide:1-48, chain:49-745, chain:155-745, chain:165-745, chain:165-278, chain:279-745
Reference Genes
BioGPS Gene:4353 MPO
COSMIC (genes):MPO MPO
CTD Gene:4353 MPO
dbSNP Gene:4353 MPO
ENSEMBL:ENSG00000005381 MPO
HGNC:7218 MPO
KEGG:hsa:4353 MPO
Monarch:4353 MPO
NCBI Gene:4353 MPO
OMIM:606989 MPO
UCSC:P05164 MPO
Reference Transcript
RefSeq:NM_000250.1 MPO
Other Identifiers
11727442_at
11727443_at
16847034
203948_PM_s_at
203948_s_at
203949_PM_at
203949_at
33284_at
3764246
3764247
3764248
3764249
3764251
3764254
3764255
3764256
3764258
3764259
3764260
3764261
3764262
3764263
3764264
3764265
3764266
3764267
3764268
3764269
3764270
3764271
3764272
3764273
3764274
3764275
3764276
3764277
3764278
4353
8016932
A_23_P141173
GE57856
GO:0001878
GO:0002149
GO:0002376
GO:0002679
GO:0003682
GO:0003824
GO:0004601
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005764
GO:0005773
GO:0006952
GO:0006979
GO:0008201
GO:0009612
GO:0016209
GO:0016491
GO:0019430
GO:0020037
GO:0030141
GO:0031410
GO:0032094
GO:0032496
GO:0034374
GO:0035578
GO:0042582
GO:0042742
GO:0042744
GO:0043066
GO:0043226
GO:0043231
GO:0046872
GO:0050832
GO:0070062
GO:0097013
GO:0098542
GO:0098754
GO:0098869
GO:1990268
HMNXSV003026676
ILMN_1705183
M19507_at
M19508_xpt3_s_at
PH_hs_0026335
TC17001727.hg
g189039_3p_a_at
g4557758_3p_at
Participates
as a member of
Azurophil granule lumen proteins [azurophil granule lumen] (Homo sapiens)
Other forms of this molecule
MPO (165-278) [azurophil granule lumen]
MPO (279-745) [extracellular region]
MPO (165-278) [extracellular region]
MPO (279-745) [phagocytic vesicle lumen]
MPO (165-278) [phagocytic vesicle lumen]
Inferred To
Homologues of MPO (279-745) [azurophil granule lumen]
(Caenorhabditis elegans)
poxA [azurophil granule lumen]
(Dictyostelium discoideum)
MPO (279-745) [azurophil granule lumen]
(Bos taurus)
MPO (279-745) [azurophil granule lumen]
(Caenorhabditis elegans)
MPO (279-745) [azurophil granule lumen]
(Canis familiaris)
MPO (279-745) [azurophil granule lumen]
(Drosophila melanogaster)
MPO (279-745) [azurophil granule lumen]
(Gallus gallus)
MPO (279-745) [azurophil granule lumen]
(Mus musculus)
MPO (279-745) [azurophil granule lumen]
(Rattus norvegicus)
MPO (279-745) [azurophil granule lumen]
(Sus scrofa)
Cross References
ZINC - World Drugs
PERM_HUMAN
Guide to Pharmacology - Targets
2789
OpenTargets
ENSG00000005381
ENSEMBL
ENSP00000225275
,
ENST00000225275
ZINC - Substances
PERM_HUMAN
ZINC - Biogenic
PERM_HUMAN
ZINC target
P05164
PRO
P05164
GlyGen
P05164
PDB
3F9P
,
4C1M
,
3ZS1
,
6BMT
,
5MFA
,
5UZU
,
1MHL
,
4DL1
,
5FIW
,
7OIH
,
4EJX
,
1DNW
,
1DNU
,
1D5L
,
1CXP
,
6AZP
,
1D2V
,
1MYP
,
1D7W
,
3ZS0
ZINC - Investigational
PERM_HUMAN
ZINC - Metabolites
PERM_HUMAN
IntEnz
1.11.2.2
HPA
ENSG00000005381-MPO
Pharos - Targets
P05164
Orphanet
MPO
ZINC - Predictions - Purchasable
PERM_HUMAN
HMDB Protein
HMDBP00282
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9UNE7 STUB1
1
STUB1 [cytosol]
(R-HSA-975970)
0.556
3
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