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The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex
Stable Identifier
R-HSA-6799202
Type
Reaction [binding]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
ReviewStatus
5/5
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Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Respiratory electron transport (Homo sapiens)
Complex I biogenesis (Homo sapiens)
The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Homo sapiens)
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The 315kDa and 370kDa subcomplexes associate to form a 550kDa complex (Mckenzie & Ryan 2010, Andrews et al. 2013).
Literature References
PubMed ID
Title
Journal
Year
20552642
Assembly factors of human mitochondrial complex I and their defects in disease
Ryan, MT
,
McKenzie, M
IUBMB Life
2010
24191001
Assembly factors for the membrane arm of human complex I
Fearnley, IM
,
Carroll, J
,
Andrews, B
,
Walker, JE
,
Ding, S
Proc. Natl. Acad. Sci. U.S.A.
2013
Participants
Input
315kDa subcomplex [mitochondrial inner membrane]
(Homo sapiens)
370 kDa subcomplex [mitochondrial inner membrane]
(Homo sapiens)
Output
550kDa complex [mitochondrial inner membrane]
(Homo sapiens)
Participates
as an event of
Complex I biogenesis (Homo sapiens)
Orthologous Events
The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Bos taurus)
The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Drosophila melanogaster)
The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Gallus gallus)
The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Mus musculus)
The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Rattus norvegicus)
The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Sus scrofa)
The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Xenopus tropicalis)
Authored
Jassal, B (2015-09-22)
Reviewed
Meldal, BH (2015-10-01)
Created
Jassal, B (2015-09-22)
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