Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex

Stable Identifier
R-HSA-6799179
Type
Reaction [binding]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
ReviewStatus
5/5
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Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex
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Subunits NDUFA12, NDUFS1, 4, 6, NDUFV1, 2 and 3 with the assembly factor NDUFAF2 comprises the peripheral arm, called the flavoprotein (FP) subcomplex. In addition, remaining subunits such as NDUFS5 join here (Mimaki et al. 2012).
Literature References
PubMed ID Title Journal Year
21924235 Understanding mitochondrial complex I assembly in health and disease

Wang, X, Ryan, MT, Thorburn, DR, McKenzie, M, Mimaki, M

Biochim. Biophys. Acta 2012
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Orthologous Events
Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Bos taurus)
Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Canis familiaris)
Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Gallus gallus)
Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Mus musculus)
Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Rattus norvegicus)
Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Sus scrofa)
Authored
Jassal, B  (2015-09-22)
Reviewed
Meldal, BH  (2015-10-01)
Created
Jassal, B  (2015-09-22)
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