Reactome | Negative gene expression regulation by 'E2F7,E2F8 dimers:E2F1 Gene [nucleoplasm]'

Negative gene expression regulation by 'E2F7,E2F8 dimers:E2F1 Gene [nucleoplasm]'

Stable Identifier

R-HSA-6798356

Type

NegativeGeneExpressionRegulation

Locations in the PathwayBrowser

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Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional Regulation by TP53 (Homo sapiens)
      - TP53 Regulates Transcription of Cell Cycle Genes (Homo sapiens)
        
        TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest (Homo sapiens)
        
        E2F7 and E2F8 homo- and heterodimers inhibit E2F1 expression (Homo sapiens)
        
        E2F7,E2F8 dimers:E2F1 Gene [nucleoplasm]

Regulation participants

Regulation type

NegativeGeneExpressionRegulation

Regulated entity

E2F7 and E2F8 homo- and heterodimers inhibit E2F1 expression

Regulator

E2F7,E2F8 dimers:E2F1 Gene [nucleoplasm]

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