TP53 binds the E2F7 gene

Stable Identifier
R-HSA-6798304
Type
Reaction
Species
Homo sapiens
Compartment
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TP53 (p53) binds the p53 response element in the promoter of the E2F7 gene (Carvajal et al. 2012, Aksoy et al. 2012).

Literature References
PubMed ID Title Journal Year
22802528 E2F7, a novel target, is up-regulated by p53 and mediates DNA damage-dependent transcriptional repression

Manfredi, JJ, Tonnessen, C, Hamard, PJ, Carvajal, LA

Genes Dev. 2012
22802529 The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence

Lowe, SW, Aksoy, O, McCurrach, M, Wang, X, Zhao, Z, Chicas, A, Zeng, T

Genes Dev. 2012
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