TP53 stimulates CASP6 expression

Stable Identifier
R-HSA-6798126
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, cytosol
ReviewStatus
5/5
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TP53 stimulates CASP6 expression
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Binding of TP53 (p53) to the third intron of the CASP6 (caspase-6) gene stimulates CASP6 expression (MacLachlan and El-Deiry 2002).
Literature References
PubMed ID Title Journal Year
12089322 Apoptotic threshold is lowered by p53 transactivation of caspase-6

MacLachlan, TK, El-Deiry, WS

Proc. Natl. Acad. Sci. U.S.A. 2002
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
p-S15,S20-TP53 Tetramer:CASP6 Gene [nucleoplasm] (Homo sapiens)
Active Unit
p-S15,S20-TP53 Tetramer [nucleoplasm]
Authored
Orlic-Milacic, M  (2015-10-14)
Reviewed
Zaccara, S  (2016-02-04)
Inga, A  (2016-02-04)
Created
Orlic-Milacic, M  (2015-09-17)
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