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BRCA1 gene [nucleoplasm]
Stable Identifier
R-HSA-6797612
Type
DNA Sequence [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by E2F6 (Homo sapiens)
BRCA1 gene expression is inhibited by E2F6 (Homo sapiens)
BRCA1 gene [nucleoplasm] (Homo sapiens)
E2F6:(TFDP1,TFDP2):BRCA1 gene [nucleoplasm] (Homo sapiens)
BRCA1 gene [nucleoplasm] (Homo sapiens)
E2F6 binds BRCA1 gene promoter (Homo sapiens)
BRCA1 gene [nucleoplasm] (Homo sapiens)
E2F6:(TFDP1,TFDP2):BRCA1 gene [nucleoplasm] (Homo sapiens)
BRCA1 gene [nucleoplasm] (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Transcription of DNA Repair Genes (Homo sapiens)
CCNK:CDK12 binds RNA Pol II at DNA repair genes (Homo sapiens)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Homo sapiens)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Homo sapiens)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Homo sapiens)
DNA repair genes regulated by CDK12 [nucleoplasm] (Homo sapiens)
BRCA1 gene [nucleoplasm] (Homo sapiens)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Homo sapiens)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Homo sapiens)
DNA repair genes regulated by CDK12 [nucleoplasm] (Homo sapiens)
BRCA1 gene [nucleoplasm] (Homo sapiens)
CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Homo sapiens)
CCNK:CDK12:CDK12-Phosphorylated Elongation Complex at DNA repair genes [nucleoplasm] (Homo sapiens)
CDK12-Phosphorylated Elongation Complex [nucleoplasm] (Homo sapiens)
CDK12-phosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Homo sapiens)
DNA repair genes regulated by CDK12 [nucleoplasm] (Homo sapiens)
BRCA1 gene [nucleoplasm] (Homo sapiens)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Homo sapiens)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Homo sapiens)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Homo sapiens)
DNA repair genes regulated by CDK12 [nucleoplasm] (Homo sapiens)
BRCA1 gene [nucleoplasm] (Homo sapiens)
CDK12 stimulates expression of DNA repair genes (Homo sapiens)
CCNK:CDK12:CDK12-Phosphorylated Elongation Complex at DNA repair genes [nucleoplasm] (Homo sapiens)
CDK12-Phosphorylated Elongation Complex [nucleoplasm] (Homo sapiens)
CDK12-phosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Homo sapiens)
DNA repair genes regulated by CDK12 [nucleoplasm] (Homo sapiens)
BRCA1 gene [nucleoplasm] (Homo sapiens)
DNA repair genes regulated by CDK12 [nucleoplasm] (Homo sapiens)
BRCA1 gene [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
ENSEMBL:ENSG00000012048 BRCA1
Gene Names
BRCA1, RNF53
Participates
as an input of
E2F6 binds BRCA1 gene promoter (Homo sapiens)
BRCA1 gene expression is inhibited by E2F6 (Homo sapiens)
as a component of
E2F6:(TFDP1,TFDP2):BRCA1 gene [nucleoplasm] (Homo sapiens)
as a member of
DNA repair genes regulated by CDK12 [nucleoplasm] (Homo sapiens)
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