MDM2 translocates to the cytosol

Stable Identifier
R-HSA-6795667
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, nucleoplasm
ReviewStatus
5/5
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MDM2 translocates to the cytosol
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Unphosphorylated MDM2 is exported from the nucleus into the cytosol (Mayo and Donner 2001).
Literature References
PubMed ID Title Journal Year
11504915 A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

Mayo, LD, Donner, DB

Proc. Natl. Acad. Sci. U.S.A. 2001
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Orthologous Events
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MDM2 translocates to the cytosol (Mus musculus)
MDM2 translocates to the cytosol (Rattus norvegicus)
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MDM2 translocates to the cytosol (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2015-10-14)
Reviewed
Zaccara, S  (2016-02-04)
Inga, A  (2016-02-04)
Created
Orlic-Milacic, M  (2015-09-04)
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