Homer dimerizes via the coiled-coil domains to form a rod with EVH1 domains on either end. It could interact with mGluRs on one end and with the other EVH1 domain can bind to Shank proteins linking the two receptors together (Hayashi et al. 2009).
Breder, CD, Petralia, RS, Tu, JC, Doan, A, Yuan, JP, Xiao, B, Ruggiero, A, Wenthold, RJ, Worley, PF, Lanahan, AA
Barnes, CA, Brakeman, PR, O'Brien, R, Huganir, RL, Worley, PF, Roche, K, Lanahan, AA
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