NLGNs binds PSD-95 subfamily members

Stable Identifier
R-HSA-6794345
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane, cytosol
ReviewStatus
5/5
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NLGNs binds PSD-95 subfamily members
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Neuroligins (NLGNs) bind to the third PDZ domain of postsynaptic density (PSD)-95 whereas NMDA receptor and K+ channels interact with the first and the second PDZ domains. The cytoplasmic domains of all three neuroligins interacts with the NH2-terminus of PSD-95 and its homologs PSD-93 and SAP102, which contains the three PDZ domains (Irie et al. 1997).
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Inferred From
Nlgn1 binds PSD-95 (Rattus norvegicus)
Authored
Garapati, P V  (2015-09-04)
Reviewed
Washbourne, P  (2015-11-09)
Created
Garapati, P V  (2015-09-04)
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