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GRM5 [plasma membrane]
Stable Identifier
R-HSA-6794276
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Metabotropic glutamate receptor 5, GRM5_HUMAN
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Protein-protein interactions at synapses (Homo sapiens)
Neurexins and neuroligins (Homo sapiens)
HOMER binds SHANK proteins (Homo sapiens)
2xHOMER1,2,3:GRM1,GRM5 [plasma membrane] (Homo sapiens)
GRM1,GRM5 [plasma membrane] (Homo sapiens)
GRM5 [plasma membrane] (Homo sapiens)
NRXNs:NLGN dimer:PSD-95:GKAP1-4:SHANK1,2,3:2xHOMER1,2,3:GRM1,5 [plasma membrane] (Homo sapiens)
2xHOMER1,2,3:GRM1,GRM5 [plasma membrane] (Homo sapiens)
GRM1,GRM5 [plasma membrane] (Homo sapiens)
GRM5 [plasma membrane] (Homo sapiens)
Homer1,2,3 binds mGluR1a,5 (Homo sapiens)
GRM1,GRM5 [plasma membrane] (Homo sapiens)
GRM5 [plasma membrane] (Homo sapiens)
HOMER1,2,3:GRM1,GRM5 [plasma membrane] (Homo sapiens)
GRM1,GRM5 [plasma membrane] (Homo sapiens)
GRM5 [plasma membrane] (Homo sapiens)
Homer1,2,3 dimerizes (Homo sapiens)
2xHOMER1,2,3:GRM1,GRM5 [plasma membrane] (Homo sapiens)
GRM1,GRM5 [plasma membrane] (Homo sapiens)
GRM5 [plasma membrane] (Homo sapiens)
HOMER1,2,3:GRM1,GRM5 [plasma membrane] (Homo sapiens)
GRM1,GRM5 [plasma membrane] (Homo sapiens)
GRM5 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P41594 GRM5
Gene Names
GRM5, GPRC1E, MGLUR5
Chain
signal peptide:1-20, chain:21-1212
Reference Genes
BioGPS Gene:2915 GRM5
COSMIC (genes):GRM5 GRM5
CTD Gene:2915 GRM5
dbSNP Gene:2915 GRM5
ENSEMBL:ENSG00000168959 GRM5
HGNC:4597 GRM5
KEGG Gene (Homo sapiens):2915 GRM5
Monarch:2915 GRM5
NCBI Gene:2915 GRM5
OMIM:604102 GRM5
UCSC:P41594 GRM5
Reference Transcript
RefSeq:XM_017017627.1 GRM5
RefSeq:XM_006718828.3 GRM5
RefSeq:NM_001143831.2 GRM5
RefSeq:NM_000842.4 GRM5
RefSeq:XM_011542792.1 GRM5
Other Identifiers
0004810273
11742420_a_at
11742421_s_at
11746641_s_at
11746642_s_at
1565389_s_at
16743130
207235_s_at
214217_at
2915
3330327
3330331
3330332
3330347
3330348
3385835
3385836
3385837
3385838
3385839
3385840
3385841
3385842
3385843
3385844
3385845
3385850
3385851
3385862
3385866
3385867
3385869
3385870
3385880
3385901
3385922
3385923
3385924
3385931
35423_at
35424_g_at
37568_at
7950921
A_23_P24361
A_24_P83899
A_33_P3275653
D28539_s_at
GE57150
GE59435
GO:0001932
GO:0003674
GO:0004930
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005886
GO:0005887
GO:0006412
GO:0006417
GO:0006448
GO:0006464
GO:0006810
GO:0007165
GO:0007186
GO:0007206
GO:0007216
GO:0007267
GO:0007268
GO:0007568
GO:0007611
GO:0007612
GO:0007626
GO:0008066
GO:0008150
GO:0009058
GO:0016020
GO:0016021
GO:0019899
GO:0030234
GO:0030296
GO:0034330
GO:0034641
GO:0035584
GO:0042592
GO:0042802
GO:0043005
GO:0043226
GO:0048169
GO:0050808
GO:0050877
GO:0050890
GO:0051966
GO:0055085
GO:0060078
GO:0061098
GO:0090647
GO:0098839
GO:0099530
GO:0099553
GO:0099566
GO:0099583
GO:1902938
GO:1904646
GO:1990782
Hs.79981.0.S1_3p_at
Hs2.410775.1.A1_3p_s_at
ILMN_1688614
ILMN_1880146
PH_hs_0022192
TC11002176.hg
TC11003285.hg
U79242_at
g4504142_3p_a_at
Participant Of
hasMember
GRM1,GRM5 [plasma membrane]
Other forms of this molecule
GRM5 [plasma membrane]
Inferred To
GRM5 [plasma membrane] (Canis familiaris)
GRM5 [plasma membrane] (Gallus gallus)
GRM5 [plasma membrane] (Sus scrofa)
grm5 [plasma membrane] (Xenopus tropicalis)
boss [plasma membrane] (Drosophila melanogaster)
grm5b [plasma membrane] (Danio rerio)
Grm5 [plasma membrane] (Mus musculus)
Grm5 [plasma membrane] (Rattus norvegicus)
Cross References
RefSeq
NP_000833.1
,
XP_011541094.1
,
NP_001137303.1
,
XP_016873116.1
,
XP_006718891.1
ZINC - World Drugs
GRM5_HUMAN
OpenTargets
ENSG00000168959
ZINC - FDA approved
GRM5_HUMAN
ZINC - Substances
GRM5_HUMAN
ZINC target
P41594
ZINC - Biogenic
GRM5_HUMAN
PRO
P41594
PDB
6N51
,
6N50
,
5CGD
,
6N4Y
,
6N52
,
6N4X
,
3LMK
,
5CGC
,
4OO9
ZINC - Investigational
GRM5_HUMAN
ZINC - Metabolites
GRM5_HUMAN
HPA
ENSG00000168959-GRM5
GeneCards
P41594
Ensembl
ENSP00000305905
,
ENST00000305447
,
ENST00000305432
,
ENSG00000168959
,
ENSP00000405690
,
ENST00000455756
,
ENSP00000306138
ZINC - Predictions - Purchasable
GRM5_HUMAN
HMDB Protein
HMDBP02180
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