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BEGAIN [cytosol]
Stable Identifier
R-HSA-6794250
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Brain-enriched guanylate kinase-associated protein, BEGIN_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q96SQ5 ZNF587
Expand all
Neuronal System (Homo sapiens)
Protein-protein interactions at synapses (Homo sapiens)
Neurexins and neuroligins (Homo sapiens)
BEGAIN binds DLG2,DLG3,DLG4 (Homo sapiens)
BEGAIN [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BUH8 BEGAIN
Gene Names
BEGAIN, KIAA1446
Chain
chain:1-593
Reference Genes
BioGPS Gene:57596 BEGAIN
COSMIC (genes):BEGAIN BEGAIN
CTD Gene:57596 BEGAIN
dbSNP Gene:57596 BEGAIN
ENSEMBL:ENSG00000183092 BEGAIN
ENSEMBL_homo_sapiens_GENE:ENSG00000183092.18 BEGAIN
HGNC:24163 BEGAIN
KEGG Gene (Homo sapiens):57596 BEGAIN
Monarch:57596 BEGAIN
NCBI Gene:57596 BEGAIN
OMIM:618597 BEGAIN
UCSC:Q9BUH8 BEGAIN
Reference Transcript
RefSeq:XM_005267921.3 BEGAIN
RefSeq:XM_017021521.1 BEGAIN
RefSeq:NM_001159531.1 BEGAIN
RefSeq:NM_020836.3 BEGAIN
Other Identifiers
11754479_a_at
16796727
220795_PM_s_at
220795_s_at
3579611
3579612
3579613
3579614
3579620
3579622
3579623
3579625
3579637
3579638
3579639
3579640
57596
70950_at
7981309
A_23_P72127
A_33_P3321205
GE87136
GO:0005515
GO:0005737
GO:0016020
GO:0045202
HMNXSV003032492
ILMN_1668924
g13124764_3p_a_at
Participates
as a component of
NMDA receptor complex:PSD-95:BEGAIN [plasma membrane] (Homo sapiens)
as an input of
BEGAIN binds DLG2,DLG3,DLG4 (Homo sapiens)
Cross References
RefSeq
NP_065887.1
,
NP_001153003.1
,
XP_016877010.1
,
XP_005267978.1
OpenTargets
ENSG00000183092
HPA
ENSG00000183092-BEGAIN
GeneCards
Q9BUH8
Ensembl
ENST00000556188
,
ENSP00000452157
,
ENSG00000183092
,
ENSP00000451397
,
ENST00000557378
,
ENSP00000450722
,
ENSP00000347301
,
ENST00000355173
,
ENST00000553553
PRO
Q9BUH8
Pharos - Targets
Q9BUH8
Interactors (35)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q6NX45 ZNF774
1
ZNF774 [nucleoplasm]
(R-HSA-3110232)
0.718
6
UniProt:Q96L14 C170L
0.669
3
UniProt:Q8TAU3 ZNF417
1
ZNF417 [nucleoplasm]
(R-HSA-1247539)
0.666
6
UniProt:Q9H0I2 ENKD1
0.666
4
UniProt:Q8BFT2
1
Haus4 [cytosol]
(R-MMU-8855202)
0.564
2
UniProt:Q3B820 F161A
0.556
3
UniProt:Q99633 PRPF18
1
PRPF18 [nucleoplasm]
(R-HSA-5688093)
0.556
3
UniProt:P26196 DDX6
1
DDX6 [cytosol]
(R-HSA-430032)
0.556
3
UniProt:P18075 BMP7
2
BMP7(30-292) [extracellular region]
(R-HSA-206223)
BMP7 [extracellular region]
(R-HSA-206257)
0.556
3
UniProt:P56524-2 HDAC4
0.556
3
UniProt:P29972 AQP1
1
AQP1 [plasma membrane]
(R-HSA-431700)
0.556
3
UniProt:P0CG20 PRR35
0.556
3
UniProt:Q8N8X9 MB213
0.556
3
UniProt:Q8IYX7 SAXO1
0.556
3
UniProt:Q86YD7 F90A1
0.556
3
UniProt:P55040 GEM
1
GEM [plasma membrane]
(R-HSA-9769962)
0.556
5
UniProt:Q96NT3-2 GUCD1
0.556
3
UniProt:Q9UJX2 CDC23
2
CDC23 [cytosol]
(R-HSA-174137)
CDC23 [nucleoplasm]
(R-HSA-174228)
0.556
3
UniProt:Q96SQ5 ZNF587
1
ZNF587 [nucleoplasm]
(R-HSA-2127565)
0.556
3
UniProt:Q9BT92 TCHP
0.556
3
UniProt:Q96IK5 GMCL1
0.556
5
UniProt:O60941-5 DTNB
0.556
3
UniProt:Q9BUZ4 TRAF4
0.556
3
UniProt:Q96EG3 ZN837
0.556
3
UniProt:Q7Z3I7 ZN572
0.556
5
UniProt:Q5T619 ZN648
0.556
5
UniProt:Q9BVG8-5 KIFC3
0.556
3
UniProt:Q8N5M1 ATPF2
0.556
5
UniProt:Q9Y2P0 ZN835
0.556
3
UniProt:Q86YV0 RASAL3
1
RASAL3 [cytosol]
(R-HSA-5658226)
0.556
3
UniProt:Q96BZ8 LENG1
1
LENG1 [nucleoplasm]
(R-HSA-9769590)
0.556
3
UniProt:Q9P2F9 ZN319
0.556
5
UniProt:Q96CV9 OPTN
6
OPTN [recycling endosome membrane]
(R-HSA-8854141)
p-S177-OPTN [nucleoplasm]
(R-HSA-2562595)
p-S177-OPTN [cytosol]
(R-HSA-2562525)
OPTN [Golgi membrane]
(R-HSA-2161111)
OPTN [cytosol]
(R-HSA-9687907)
p-S177,S473,S513-OPTN [cytosol]
(R-HSA-9687840)
0.556
3
UniProt:P28749 RBL1
2
RBL1 [nucleoplasm]
(R-HSA-389104)
p-T369,S640,S964,S975-RBL1 [nucleoplasm]
(R-HSA-1226085)
0.508
2
UniProt:Q5VTD9 GFI1B
0.488
2
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