Reactome | LHB [Golgi lumen]

LHB [Golgi lumen]

Stable Identifier

R-HSA-6793932

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi lumen

Synonyms

Lutropin subunit beta, LSHB_HUMAN

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Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Transport to the Golgi and subsequent modification (Homo sapiens)
      - N-glycan antennae elongation in the medial/trans-Golgi (Homo sapiens)
        
        Reactions specific to the complex N-glycan synthesis pathway (Homo sapiens)
        
        CHST8 transfers SO4(2-) from PAPS to glyco-Lutropin (Homo sapiens)
        
        glyco-Lutropin [Golgi lumen] (Homo sapiens)
        
        LHB [Golgi lumen] (Homo sapiens)

External Reference Information

External Reference

UniProt:P01229 LHB

Gene Names

LHB

Chain

signal peptide:1-20, chain:21-141

Reference Genes

BioGPS Gene:3972 LHB

COSMIC (genes):LHB LHB

CTD Gene:3972 LHB

dbSNP Gene:3972 LHB

ENSEMBL:ENSG00000104826 LHB

ENSEMBL_homo_sapiens_GENE:ENSG00000104826.15 LHB

HGNC:6584 LHB

KEGG Gene (Homo sapiens):3972 LHB

Monarch:3972 LHB

NCBI Gene:3972 LHB

OMIM:152780 LHB

UCSC:P01229 LHB

Reference Transcript

RefSeq:NM_000894.2 LHB

Other Identifiers

11715313_s_at

214471_3p_x_at

214471_PM_x_at

214471_x_at

35378_at

3867574

3867575

3867576

3867578

3867616

3867640

3972

697_f_at

8038278

A_23_P218505

GE558199

GO:0005102

GO:0005179

GO:0005515

GO:0005576

GO:0005615

GO:0005737

GO:0005794

GO:0005796

GO:0006629

GO:0006701

GO:0007165

GO:0007186

GO:0007267

GO:0008584

GO:0009755

GO:0022414

GO:0023052

GO:0043226

GO:0048018

GO:0048856

GO:0061696

GO:0098772

HMNXSV003001944

Hs.154704.0.S1_3p_at

Hs.154704.0.S1_3p_x_at

ILMN_1765187

PH_hs_0029247

TC19001704.hg

Participates

as a component of

glyco-Lutropin [Golgi lumen] (Homo sapiens)

Other forms of this molecule

S-glyco-LHB [Golgi lumen]

LHB [extracellular region]

Inferred To

lhb [Golgi lumen] (Danio rerio)

Lhb [Golgi lumen] (Mus musculus)

Lhb [Golgi lumen] (Rattus norvegicus)

LHB [Golgi lumen] (Bos taurus)

LHB [Golgi lumen] (Sus scrofa)

Modified Residues

Name

glycosylated residue (N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl group) at 50

Coordinate

Modification

N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl group

PsiMod Name

glycosylated residue

PsiMod Definition

A protein modification that effectively replaces a hydrogen atom with an carbohydrate-like group through a glycosidic bond.

Cross References

RefSeq

NP_000885.1

OpenTargets

ENSG00000104826

GeneCards

P01229

HPA

ENSG00000104826-LHB

Ensembl

ENSP00000497294, ENST00000649238, ENSG00000104826

PRO

P01229

Pharos - Targets

P01229

Orphanet

16353

Interactors (3)

Accession	Confidence Score	Evidence (IntAct)
UniProt:Q96EQ0 SGTB	0.556	3
UniProt:Q9P121-3 NTM	0.556	3
UniProt:Q13643 FHL3	0.556	3

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