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RNMTL1 [mitochondrial matrix]
Stable Identifier
R-HSA-6793067
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
fullName evidence="9"rRNA methyltransferase 3, mitochondrial ecNumber evidence="12 13"2.1.1.-/ecNumber, MRM3_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the mitochondrion (Homo sapiens)
rRNA modification in the mitochondrion (Homo sapiens)
MRM3 (RNMTL1) methylates guanosine-1370 of 16S rRNA yielding 2'-O-methylguanosine-1370 (Homo sapiens)
RNMTL1 [mitochondrial matrix] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9HC36 MRM3
Gene Names
MRM3, RNMTL1, HC90
Chain
transit peptide:1-40, chain:41-420
Reference Genes
BioGPS Gene:55178 MRM3
COSMIC (genes):MRM3 MRM3
CTD Gene:55178 MRM3
dbSNP Gene:55178 MRM3
ENSEMBL:ENSG00000171861 MRM3
ENSEMBL_homo_sapiens_GENE:ENSG00000171861.11 MRM3
HGNC:18485 MRM3
KEGG Gene (Homo sapiens):55178 MRM3
Monarch:55178 MRM3
NCBI Gene:55178 MRM3
OMIM:612600 MRM3
UCSC:Q9HC36 MRM3
Reference Transcript
RefSeq:NM_018146.3 MRM3
RefSeq:NM_001317947.1 MRM3
Other Identifiers
11720329_at
16829498
218993_PM_at
218993_at
3238170
3705541
3705542
3705543
3705546
3705548
3705549
51642_at
55178
8003621
A_23_P135357
GE80140
GO:0000451
GO:0003723
GO:0003824
GO:0005515
GO:0005737
GO:0005739
GO:0005759
GO:0006364
GO:0006396
GO:0008168
GO:0008173
GO:0016740
GO:0032259
GO:0042254
GO:0042802
GO:0043226
GO:0070039
GO:0140098
HMNXSV003031859
ILMN_1689652
PH_hs_0010785
TC17000005.hg
g8922533_3p_at
Cross References
RefSeq
NP_060616.1
,
NP_001304876.1
OpenTargets
ENSG00000171861
GeneCards
Q9HC36
HPA
ENSG00000171861-MRM3
Ensembl
ENSG00000171861
,
ENST00000304478
,
ENSP00000306080
PRO
Q9HC36
Pharos - Targets
Q9HC36
PDB
7OI6
Interactors (28)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P0DTC9 N
13
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane]
(R-COV-9729325)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus]
(R-COV-9729339)
N [plasma membrane]
(R-COV-9694356)
SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol]
(R-COV-9756489)
N [cytosol]
(R-COV-9694300)
p-S188,206-N [cytosol]
(R-COV-9729324)
p-8S-N [cytosol]
(R-COV-9729335)
p-8S,2T-N [cytosol]
(R-COV-9729277)
p-11S,2T-N [cytosol]
(R-COV-9729264)
p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729308)
ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729275)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9729341)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729340)
0.768
5
UniProt:Q13643 FHL3
0.718
8
UniProt:Q8WVV5 BTN2A2
1
BTN2A2 [plasma membrane]
(R-HSA-8851047)
0.556
3
UniProt:Q14162 SCARF1
2
SCARF1 [plasma membrane]
(R-HSA-2197636)
SCARF1 [endocytic vesicle membrane]
(R-HSA-2239453)
0.556
3
UniProt:Q9HC36 MRM3
1
RNMTL1 [mitochondrial matrix]
(R-HSA-6793067)
0.556
3
UniProt:Q9Y5Z9 UBIAD1
1
UBIAD1 [endoplasmic reticulum membrane]
(R-HSA-2980965)
0.556
3
UniProt:Q9NVV5-2 AIG1
0.556
3
UniProt:Q10471 GALNT2
2
GALNT2(1-571) [endoplasmic reticulum membrane]
(R-HSA-8849322)
GALNT2(1-571) [Golgi membrane]
(R-HSA-913618)
0.556
3
UniProt:P01375 TNF
5
TNF(52-76) [extracellular region]
(R-HSA-8863375)
TNF(1-34) [plasma membrane]
(R-HSA-8863367)
TNF(1-76) [plasma membrane]
(R-HSA-8863120)
TNF(77-233) [extracellular region]
(R-HSA-976821)
TNF(1-233) [plasma membrane]
(R-HSA-66220)
0.556
3
UniProt:Q8N5M9 JAGN1
0.556
3
UniProt:O95159 ZFPL1
0.556
3
UniProt:P30301 MIP
1
MIP [plasma membrane]
(R-HSA-432026)
0.556
3
UniProt:Q05329 GAD2
2
PXLP-K396-GAD2 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
(R-HSA-888582)
PXLP-K396-GAD2 [plasma membrane]
(R-HSA-936509)
0.556
3
UniProt:Q8WVX3-2 C4ORF3
0.556
3
UniProt:Q13084 MRPL28
1
MRPL28 [mitochondrial inner membrane]
(R-HSA-5368246)
0.527
2
UniProt:Q96EH3 MASU1
0.527
2
UniProt:Q9Y6G3 MRPL42
1
MRPL42 [mitochondrial inner membrane]
(R-HSA-5368237)
0.527
3
UniProt:Q8N5N7 MRPL50
1
MRPL50 [mitochondrial inner membrane]
(R-HSA-5368181)
0.527
3
UniProt:O75439 PMPCB
1
PMPCB [mitochondrial matrix]
(R-HSA-1299434)
0.527
2
UniProt:Q9P2K6 KLHL42
1
KLHL42 [cytosol]
(R-HSA-8863204)
0.527
2
UniProt:O75380 NDUFS6
1
NDUFS6 [mitochondrial inner membrane]
(R-HSA-163922)
0.527
2
UniProt:P23786 CPT2
1
CPT2 [mitochondrial inner membrane]
(R-HSA-200994)
0.527
2
UniProt:Q96T88 UHRF1
2
UHRF1 [cytosol]
(R-HSA-9818452)
UHRF1 [nucleoplasm]
(R-HSA-212103)
0.527
2
UniProt:P46199 MTIF2
1
MTIF2 [mitochondrial matrix]
(R-HSA-5368271)
0.527
2
UniProt:Q9NP92 MRPS30
1
MRPS30 [mitochondrial inner membrane]
(R-HSA-5368258)
0.527
4
UniProt:Q8N5M1 ATPF2
0.527
2
UniProt:Q10713 PMPCA
1
PMPCA [mitochondrial matrix]
(R-HSA-1299450)
0.527
2
UniProt:Q9BVS5 TRMT61B
1
TRMT61B [mitochondrial matrix]
(R-HSA-6787512)
0.483
2
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