CCNG1 recruits PP2A-PPP2R5C to MDM2

Stable Identifier
R-HSA-6792871
Type
Reaction
Species
Homo sapiens
Compartment
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CCNG1 (cyclin G1) simultaneously interacts with the regulatory subunit of the PP2A protein phosphatase complex, PPP2R5C (Okamoto et al. 1996), and MDM2, thus recruiting the PP2A complex to MDM2 (Okamoto et al. 2002).

Literature References
PubMed ID Title Journal Year
11983168 Cyclin G recruits PP2A to dephosphorylate Mdm2

Taya, Y, Li, H, Jensen, MR, Prives, C, Thorgeirsson, SS, Zhang, T, Okamoto, K

Mol. Cell 2002
8887688 p53-dependent association between cyclin G and the B' subunit of protein phosphatase 2A

Serrano, M, Kamibayashi, C, Mumby, MC, Okamoto, K, Prives, C, Beach, D

Mol. Cell. Biol. 1996
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