CCNG1 recruits PP2A-PPP2R5C to MDM2

Stable Identifier
R-HSA-6792871
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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CCNG1 (cyclin G1) simultaneously interacts with the regulatory subunit of the PP2A protein phosphatase complex, PPP2R5C (Okamoto et al. 1996), and MDM2, thus recruiting the PP2A complex to MDM2 (Okamoto et al. 2002).

Literature References
PubMed ID Title Journal Year
8887688 p53-dependent association between cyclin G and the B' subunit of protein phosphatase 2A

Okamoto, K, Kamibayashi, C, Serrano, M, Prives, C, Mumby, MC, Beach, D

Mol. Cell. Biol. 1996
11983168 Cyclin G recruits PP2A to dephosphorylate Mdm2

Okamoto, K, Li, H, Jensen, MR, Zhang, T, Taya, Y, Thorgeirsson, SS, Prives, C

Mol. Cell 2002
Participants
Participant Of
Orthologous Events
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Reviewed
Created