TP53 stimulates CCNG1 gene expression

Stable Identifier
R-HSA-6792491
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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TP53 stimulates CCNG1 gene expression
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Upon binding to the p53 response elements in the promoter and/or the first intron of CCNG1 (cyclin G1) gene, TP53 induces CCNG1 transcription (Okamoto and Beach 1994, Zauberman et al. 1995, Endo et al. 1996).

Literature References
PubMed ID Title Journal Year
8954786 Structure and chromosomal assignment of the human cyclin G gene

Fujita, T, Endo, Y, Tsuruga, H, Tamura, K, Nojima, H

Genomics 1996
7784084 Identification of p53 target genes through immune selection of genomic DNA: the cyclin G gene contains two distinct p53 binding sites

Zauberman, A, Oren, M, Lupo, A

Oncogene 1995
7957050 Cyclin G is a transcriptional target of the p53 tumor suppressor protein

Okamoto, K, Beach, D

EMBO J. 1994
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
TP53 Tetramer:CCNG1 Gene [nucleoplasm] (Homo sapiens)
Active Unit
TP53 Tetramer [nucleoplasm]
Authored
Orlic-Milacic, M  (2015-10-14)
Reviewed
Zaccara, S  (2016-02-04)
Inga, A  (2016-02-04)
Created
Orlic-Milacic, M  (2015-08-24)
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