Reactome | TSR1 [cytosol]

TSR1 [cytosol]

Stable Identifier

R-HSA-6791570

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Pre-rRNA-processing protein TSR1 homolog, TSR1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q2NL82 TSR1

Gene Names

TSR1, KIAA1401

Chain

chain:1-804

Reference Genes

BioGPS Gene:55720 TSR1

COSMIC (genes):TSR1 TSR1

CTD Gene:55720 TSR1

dbSNP Gene:55720 TSR1

ENSEMBL:ENSG00000167721 TSR1

ENSEMBL_homo_sapiens_GENE:ENSG00000167721.11 TSR1

HGNC:25542 TSR1

KEGG Gene (Homo sapiens):55720 TSR1

Monarch:55720 TSR1

NCBI Gene:55720 TSR1

OMIM:611214 TSR1

UCSC:Q2NL82 TSR1

Reference Transcript

RefSeq:NM_018128.4 TSR1

Other Identifiers

11732142_at

11732143_at

16839582

218155_3p_x_at

218155_PM_x_at

218155_x_at

218156_PM_s_at

218156_s_at

221987_PM_s_at

221987_s_at

235677_PM_at

235677_at

239042_3p_at

239042_PM_at

239042_at

3740997

3740999

3741000

3741001

3741002

3741003

3741005

3741006

3741007

3741009

3741010

3741012

3741013

3741014

3741016

3741018

3741019

3741020

3741021

3741022

3741023

3741024

3741026

40982_at

44830_at

55720

8011245

88203_at

A_23_P107087

A_24_P941336

GE82305

GO:0000462

GO:0000479

GO:0003723

GO:0003824

GO:0003924

GO:0005515

GO:0005525

GO:0005634

GO:0005654

GO:0005730

GO:0005829

GO:0016787

GO:0030688

GO:0034511

GO:0042254

GO:0043226

HMNXSV003057536

Hs.194364.0.A1_3p_at

Hs.194364.0.A1_3p_x_at

Hs.204501.0.A2_3p_at

Hs.204501.0.A2_3p_s_at

Hs.204501.0.A2_3p_x_at

Hs.27335.1.A1_3p_s_at

Hs.289386.0.A1_3p_at

ILMN_1775761

ILMN_2092232

PH_hs_0024453

TC17000991.hg

Participates

as an output of

18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol (Homo sapiens)

Other forms of this molecule

TSR1 [nucleoplasm]

Inferred To

Tsr1 [cytosol] (Drosophila melanogaster)

Tsr1 [cytosol] (Mus musculus)

Tsr1 [cytosol] (Rattus norvegicus)

LOC610048 [cytosol] (Canis familiaris)

tag-151 [cytosol] (Caenorhabditis elegans)

TSR1 [cytosol] (Bos taurus)

Cross References

RefSeq

NP_060598.3

OpenTargets

ENSG00000167721

HPA

ENSG00000167721-TSR1

GeneCards

Q2NL82

Ensembl

ENST00000301364, ENSG00000167721, ENSP00000301364

PRO

Q2NL82

Pharos - Targets

Q2NL82

PDB

7WTV, 7WTU, 6G18, 7WTW, 6G51, 6G4W, 6ZN5, 7WU0, 7WTT, 6ZMT, 6G53, 7WTS, 7WTX, 7WTZ, 6G4S

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96GA3 LTV1	2	LTV1 [nucleoplasm] (R-HSA-6791566) LTV1 [cytosol] (R-HSA-6791520)	0.643	5
UniProt:P49790 NUP153	1	NUP153 [nucleoplasm] (R-HSA-157695)	0.643	3
UniProt:Q5JTH9 RRP12			0.643	3
UniProt:Q14974 KPNB1	5	KPNB1 [specific granule lumen] (R-HSA-6799646) KPNB1 [extracellular region] (R-HSA-6806306) KPNB1 [ficolin-1-rich granule lumen] (R-HSA-6800978) KPNB1 [cytosol] (R-HSA-180733) KPNB1 [nucleoplasm] (R-HSA-180714)	0.643	5
UniProt:Q13895 BYSL	2	BYSL [nucleoplasm] (R-HSA-6791526) BYSL [cytosol] (R-HSA-6791518)	0.643	5
UniProt:P62263 RPS14	2	RPS14 [nucleoplasm] (R-HSA-6790669) RPS14 [cytosol] (R-HSA-72333)	0.643	3
UniProt:P62753 RPS6	4	RPS6 [nucleoplasm] (R-HSA-6790606) 3OHR147-RPS6 [cytosol] (R-HSA-9629876) p-5S-RPS6 [cytosol] (R-HSA-165727) RPS6 [cytosol] (R-HSA-72381)	0.615	3
UniProt:Q6NTF9-3 Q6NTF93			0.556	3
UniProt:Q9UHD4 CIDEB			0.556	3
UniProt:P39019 RPS19	2	RPS19 [nucleoplasm] (R-HSA-6798710) RPS19 [cytosol] (R-HSA-72343)	0.527	2
UniProt:P62277 RPS13	2	RPS13 [nucleoplasm] (R-HSA-6791198) RPS13 [cytosol] (R-HSA-72331)	0.527	2
UniProt:Q8WVZ9 KBTBD7	1	KBTBD7 [cytosol] (R-HSA-5658415)	0.527	2
UniProt:P23396 RPS3	2	RPS3 [nucleoplasm] (R-HSA-6798714) RPS3 [cytosol] (R-HSA-72369)	0.527	2
UniProt:P19784 CSNK2A2	2	CSNK2A2 [nucleoplasm] (R-HSA-6805065) CSNK2A2 [cytosol] (R-HSA-201721)	0.527	2
UniProt:P08865 RPSA	2	RPSA [nucleoplasm] (R-HSA-6798722) RPSA [cytosol] (R-HSA-72389)	0.527	2
UniProt:P15880 RPS2	3	RPS2 [nucleoplasm] (R-HSA-6790655) Me2aR-RPS2 [cytosol] (R-HSA-8879138) RPS2 [cytosol] (R-HSA-72347)	0.527	2
UniProt:Q00839 HNRNPU	1	HNRNPU [nucleoplasm] (R-HSA-71953)	0.527	2
UniProt:O95453 PARN	1	PARN [cytosol] (R-HSA-430009)	0.527	2
UniProt:P62241 RPS8	2	RPS8 [nucleoplasm] (R-HSA-6791203) RPS8 [cytosol] (R-HSA-72385)	0.527	2
UniProt:P62249 RPS16	2	RPS16 [nucleoplasm] (R-HSA-6791196) RPS16 [cytosol] (R-HSA-72337)	0.527	4

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