Reactome | RIOK2 [cytosol]

RIOK2 [cytosol]

Stable Identifier

R-HSA-6791533

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Serine/threonine-protein kinase RIO2 ecNumber2.7.11.1/ecNumber, RIOK2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9BVS4 RIOK2

Gene Names

RIOK2, RIO2

Chain

chain:1-552

Reference Genes

BioGPS Gene:55781 RIOK2

COSMIC (genes):RIOK2 RIOK2

CTD Gene:55781 RIOK2

dbSNP Gene:55781 RIOK2

ENSEMBL:ENSG00000058729 RIOK2

ENSEMBL_homo_sapiens_GENE:ENSG00000058729.11 RIOK2

HGNC:18999 RIOK2

KEGG Gene (Homo sapiens):55781 RIOK2

Monarch:55781 RIOK2

NCBI Gene:55781 RIOK2

OMIM:617754 RIOK2

UCSC:Q9BVS4 RIOK2

Reference Transcript

Other Identifiers

11723452_s_at

11723453_a_at

11723454_at

16998421

218535_PM_s_at

218535_s_at

222663_PM_at

222663_at

2868284

2868285

2868286

2868287

2868288

2868291

2868292

2868293

2868294

2868295

2868296

2868297

2868298

2868299

2868301

2868302

2868304

2868305

2868306

43998_at

55781

56793_at

8113286

A_21_P0000023

A_24_P234822

GE82351

GO:0000166

GO:0000278

GO:0003824

GO:0004672

GO:0004674

GO:0005515

GO:0005524

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006468

GO:0006913

GO:0007049

GO:0007059

GO:0016301

GO:0016310

GO:0016740

GO:0030071

GO:0030490

GO:0030688

GO:0036211

GO:0042254

GO:0042274

GO:0043226

GO:0046777

GO:0046872

GO:0106310

GO:0140096

GO:2000208

GO:2000234

HMNXSV003048806

Hs.27021.0.S2_3p_at

ILMN_1655329

PH_hs_0002395

TC05001621.hg

g8922904_3p_a_at

Participates

as an output of

18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol (Homo sapiens)

Other forms of this molecule

RIOK2 [nucleoplasm]

Inferred To

RIOK2 [cytosol] (Bos taurus)

RIOK2 [cytosol] (Caenorhabditis elegans)

RIOK2 [cytosol] (Canis familiaris)

RIOK2 [cytosol] (Drosophila melanogaster)

RIOK2 [cytosol] (Gallus gallus)

RIOK2 [cytosol] (Mus musculus)

RIOK2 [cytosol] (Rattus norvegicus)

riok2 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_060813.2, NP_001153221.1

ZINC - World Drugs

RIOK2_HUMAN

Guide to Pharmacology - Targets

2187

OpenTargets

ENSG00000058729

ZINC - FDA approved

RIOK2_HUMAN

ZINC - Substances

RIOK2_HUMAN

ZINC target

Q9BVS4

ZINC - Biogenic

RIOK2_HUMAN

PRO

Q9BVS4

PDB

7WU0, 6G51, 6G18, 6FDM, 6FDO, 7VBT, 6HK6, 6FDN, 5DHF

ZINC - Investigational

RIOK2_HUMAN

HPA

ENSG00000058729-RIOK2

GeneCards

Q9BVS4

Ensembl

ENST00000283109, ENSP00000420932, ENSG00000058729, ENSP00000283109, ENST00000508447

Pharos - Targets

Q9BVS4

ZINC - Predictions - Purchasable

RIOK2_HUMAN

HMDB Protein

HMDBP01133

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
IntAct:EBI-22312375 CCSB ORF ID			0.556	3
UniProt:Q13895 BYSL	2	BYSL [nucleoplasm] (R-HSA-6791526) BYSL [cytosol] (R-HSA-6791518)	0.527	3