TP53 binds the APAF1 gene promoter

Stable Identifier
R-HSA-6791349
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
TP53 binds the APAF1 gene promoter
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
TP53 (p53) binds the p53 response element in the promoter of the APAF1 gene (Robles et al. 2001).
Literature References
PubMed ID Title Journal Year
11559530 APAF-1 is a transcriptional target of p53 in DNA damage-induced apoptosis

Bemmels, NA, Robles, AI, Harris, CC, Foraker, AB

Cancer Res. 2001
Participants
Input
Output
Participates
as an event of
Authored
Orlic-Milacic, M  (2015-10-14)
Reviewed
Zaccara, S  (2016-02-04)
Inga, A  (2016-02-04)
Created
Orlic-Milacic, M  (2015-08-20)
Cite Us!