Reactome | RPS5 [nucleoplasm]

RPS5 [nucleoplasm]

Stable Identifier

R-HSA-6791188

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

40S ribosomal protein S5 component recommendedName: 40S ribosomal protein S5, N-terminally processed /component, RS5_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P46782 RPS5

Gene Names

RPS5

Chain

initiator methionine:1, chain:1-204, chain:2-204

Reference Genes

BioGPS Gene:6193 RPS5

COSMIC (genes):RPS5 RPS5

CTD Gene:6193 RPS5

dbSNP Gene:6193 RPS5

ENSEMBL:ENSG00000083845 RPS5

HGNC:10426 RPS5

KEGG Gene (Homo sapiens):6193 RPS5

Monarch:6193 RPS5

NCBI Gene:6193 RPS5

OMIM:603630 RPS5

UCSC:P46782 RPS5

Reference Transcript

RefSeq:NM_001009.3 RPS5

Other Identifiers

0007040315

11716040_a_at

11756251_x_at

11757028_s_at

16866282

18671254

18671255

18671256

18671257

18671258

18671259

18671260

200024_PM_at

200024_at

2971002

32437_at

3844016

3844017

3844018

3844019

3844020

3844021

3844023

3844024

3844026

3844027

3844028

3844029

3844031

3844033

3998374

6193

63954_at

63955_g_at

7892835

7893600

7894513

7894732

7895001

7895190

7895975

7896434

8031933

A_23_P208265

A_33_P3300817

GO:0000028

GO:0000184

GO:0002181

GO:0003674

GO:0003723

GO:0003729

GO:0003735

GO:0005198

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005840

GO:0005925

GO:0006412

GO:0006413

GO:0006450

GO:0006605

GO:0006614

GO:0006810

GO:0008150

GO:0009056

GO:0009058

GO:0015031

GO:0015935

GO:0016020

GO:0019083

GO:0019843

GO:0022607

GO:0022618

GO:0022626

GO:0022627

GO:0032991

GO:0034641

GO:0034655

GO:0042254

GO:0043226

GO:0044403

GO:0065003

GO:0070062

GO:1990904

HMNXSV003041433

ILMN_1707810

PH_hs_0029945

TC19000964.hg

TC19002270.hg

U14970_at

g4506728_3p_at

Participates

as a component of

18SE pre-40S particle [nucleoplasm] (Homo sapiens)

This entity regulates

Positively

30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA (Homo sapiens)

Other forms of this molecule

RPS5 [cytosol]

Inferred To

rps5 [nucleoplasm] (Danio rerio)

rps5 [nucleoplasm] (Dictyostelium discoideum)

rps5 [nucleoplasm] (Schizosaccharomyces pombe)

rps5 [nucleoplasm] (Xenopus tropicalis)

Homologues of RPS5 [nucleoplasm] (Schizosaccharomyces pombe)

RpS5b [nucleoplasm] (Drosophila melanogaster)

Rps5 [nucleoplasm] (Mus musculus)

Rps5 [nucleoplasm] (Rattus norvegicus)

rps-5 [nucleoplasm] (Caenorhabditis elegans)

Ghost homologue of RPS5 [nucleoplasm] (Bos taurus)

rps502 [nucleoplasm] (Schizosaccharomyces pombe)

RPS5 [nucleoplasm] (Canis familiaris)

RPS5 [nucleoplasm] (Plasmodium falciparum)

RPS5 [nucleoplasm] (Saccharomyces cerevisiae)

Cross References

RefSeq

NP_001000.2

OpenTargets

ENSG00000083845

HPA

ENSG00000083845-RPS5

GeneCards

P46782

Ensembl

ENST00000596046, ENST00000196551, ENSP00000472985, ENST00000601521, ENSP00000470114, ENSP00000196551, ENSG00000083845

PRO

P46782

Pharos - Targets

P46782

GlyGen

P46782

PDB

6G4S, 6OLE, 6G18, 6Y2L, 6G51, 6OLF, 6G53, 6YBS, 6G4W, 6ZMO, 6OLG, 5OA3, 6ZMT, 6Z6L, 5AJ0, 6OLI, 5T2C, 6OM0, 6ZXD, 6ZMW, 6Z6M, 7K5I, 6OLZ, 6OM7, 6ZN5, 6G5H, 6ZXE, 5LKS, 6Z6N, 6G5I, 6ZXF, 6ZUO, 7MQ8, 6ZXG, 6ZV6, 5FLX, 6FEC, 7MQ9, 4V6X, 6ZXH, 7MQA, 6Y0G, 5A2Q, 6ZVH, 6ZVJ, 7A09, 5VYC, 6Y57, 6QZP, 4UG0, 6ZLW, 6ZOJ, 6IP6, 6ZM7, 6IP5, 6ZOL, 6ZON, 6IP8, 6ZP4, 6ZME, 6ZMI, 6XA1

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P63244 RACK1	1	GNB2L1 [cytosol] (R-HSA-5626956)	0.607	3
UniProt:P54253 ATX1			0.556	3
UniProt:Q8WXH2 JPH3			0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3