Release of NS1 homodimer

Stable Identifier
R-HSA-6791035
Type
Reaction
Species
Homo sapiens
Related Species
Influenza A virus
Compartment
nucleoplasm
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Release of NS1 homodimer
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Once the NS1 homodimer is imported into the nucleus, the importin complex releases the NS1 homodimer.

Literature References
PubMed ID Title Journal Year
10205180 Influenza A virus NS1 protein targets poly(A)-binding protein II of the cellular 3'-end processing machinery

Chen, Z, Krug, RM, Li, Y

EMBO J 1999
10846107 Influenza virus NS1 protein counteracts PKR-mediated inhibition of replication

Bergmann, M, Pehamberger, H, Carnero, E, Wolff, K, Muster, T, Garcia-Sastre, A, Palese, P

J. Virol. 2000
9651582 Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3'end formation of cellular pre-mRNAs

Krug, RM, Keller, W, Li, Y, Barabino, SM, Nemeroff, ME

Mol Cell 1998
8313914 Influenza virus NS1 protein inhibits pre-mRNA splicing and blocks mRNA nucleocytoplasmic transport

Beloso, A, Ortin, J, Fortes, P

EMBO J 1994
Participants
Input
Output
Participates
as an event of
Disease
Name Identifier Synonyms
influenza DOID:8469 Influenza with other manifestations (disorder), Influenza with other manifestations NOS (disorder), flu, Influenza with other manifestations, Influenza with non-respiratory manifestation (disorder), influenza with non-respiratory manifestation
Authored
Gillespie, ME  (2013-11-18)
Reviewed
Gale M, Jr  (2004-05-12)
Created
Gillespie, ME  (2015-08-17)
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