Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
SFTPB binds itself
Stable Identifier
R-HSA-6791016
Type
Reaction [binding]
Species
Homo sapiens
Compartment
multivesicular body lumen
Synonyms
SFTPB dimerises
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Surfactant metabolism (Homo sapiens)
SFTPB binds itself (Homo sapiens)
General
SBML
|
BioPAX
Level 2
Level 3
|
PDF
SVG
|
PNG
Low
Medium
High
|
PPTX
|
SBGN
Click the image above or
here
to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
After pro-SFTPB is cleaved, the resultant mature peptide SFTPB (chain 201-279) forms a dimeric, disulfide linked protein (Johansson et al. 1992) and is trafficked to lamellar bodies.
Literature References
PubMed ID
Title
Journal
Year
1568474
Human surfactant polypeptide SP-B. Disulfide bridges, C-terminal end, and peptide analysis of the airway form
Johansson, J
,
Jörnvall, H
,
Curstedt, T
FEBS Lett.
1992
Participants
Input
x 2
SFTPB(201-279) [multivesicular body lumen]
(Homo sapiens)
Output
SFTPB dimer [multivesicular body lumen]
(Homo sapiens)
Participates
as an event of
Surfactant metabolism (Homo sapiens)
Orthologous Events
SFTPB binds itself (Bos taurus)
SFTPB binds itself (Caenorhabditis elegans)
SFTPB binds itself (Canis familiaris)
SFTPB binds itself (Dictyostelium discoideum)
SFTPB binds itself (Drosophila melanogaster)
SFTPB binds itself (Gallus gallus)
SFTPB binds itself (Mus musculus)
SFTPB binds itself (Rattus norvegicus)
SFTPB binds itself (Sus scrofa)
Authored
Jassal, B (2015-08-17)
Reviewed
D'Eustachio, P (2015-08-17)
Created
Jassal, B (2015-08-17)
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text