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DIEXF [nucleoplasm]
Stable Identifier
R-HSA-6790689
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Digestive organ expansion factor homolog, DIEXF_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the nucleus and cytosol (Homo sapiens)
Major pathway of rRNA processing in the nucleolus and cytosol (Homo sapiens)
21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA (Homo sapiens)
18SE pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
DIEXF [nucleoplasm] (Homo sapiens)
21S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
DIEXF [nucleoplasm] (Homo sapiens)
30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA (Homo sapiens)
21S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
DIEXF [nucleoplasm] (Homo sapiens)
30S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
DIEXF [nucleoplasm] (Homo sapiens)
45S pre-rRNA is nucleolytically processed at site 2 (site 2b) to yield 30S pre-rRNA and 32S pre-rRNA (Homo sapiens)
30S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
DIEXF [nucleoplasm] (Homo sapiens)
45S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
DIEXF [nucleoplasm] (Homo sapiens)
47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA (Homo sapiens)
45S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
DIEXF [nucleoplasm] (Homo sapiens)
47S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
DIEXF [nucleoplasm] (Homo sapiens)
rRNA modification in the nucleus and cytosol (Homo sapiens)
EMG1 of the SSU processome methylates pseudouridine-1248 of 18S rRNA yielding N(1)-methylpseudouridine-1248 (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
DIEXF [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q68CQ4 UTP25
Gene Names
UTP25, C1orf107, DEF, DIEXF
Chain
chain:1-756
Reference Genes
BioGPS Gene:27042 UTP25
COSMIC (genes):UTP25 UTP25
CTD Gene:27042 UTP25
dbSNP Gene:27042 UTP25
ENSEMBL:ENSG00000117597 DIEXF
ENSEMBL_homo_sapiens_GENE:ENSG00000117597.18 UTP25
HGNC:28440 UTP25
KEGG Gene (Homo sapiens):27042 UTP25
Monarch:27042 UTP25
NCBI Gene:27042 UTP25
OMIM:619663 UTP25
UCSC:Q68CQ4 UTP25
Reference Transcript
RefSeq:NM_014388.6 UTP25
Other Identifiers
11728258_at
11728259_a_at
11728260_at
16677037
204699_PM_s_at
204699_s_at
204700_PM_x_at
204700_x_at
214193_PM_s_at
214193_s_at
220251_PM_at
220251_at
2378200
2378201
2378202
2378203
2378205
2378206
2378207
2378208
2378209
2378210
2378214
2378215
2378217
2378219
2378220
2378223
2378225
2378233
2378234
2378235
2378236
2378237
2378238
2378239
2378240
2378241
2378242
2378243
2378244
2378245
2378246
2378247
27042
33734_at
7909478
A_14_P139185
A_14_P139450
A_23_P34946
A_23_P34953
A_23_P46337
A_24_P385341
GE81923
GE83035
GO:0000462
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005730
GO:0006364
GO:0019843
GO:0030163
GO:0031648
GO:0032040
GO:0034511
GO:0040019
GO:0042254
GO:0043226
GO:0048568
GO:0048856
GO:1902570
HMNXSV003027415
Hs.173381.1.A1_3p_s_at
Hs.194754.0.S1_3p_a_at
ILMN_1746677
ILMN_2089656
PH_hs_0011521
PH_hs_0035679
TC01001752.hg
g13376508_3p_at
Participates
as a component of
SSU Processome [nucleoplasm] (Homo sapiens)
Inferred To
UTP25 [nucleoplasm]
(Bos taurus)
UTP25 [nucleoplasm]
(Canis familiaris)
UTP25 [nucleoplasm]
(Saccharomyces cerevisiae)
UTP25 [nucleoplasm]
(Sus scrofa)
Dmel\CG3735 [nucleoplasm]
(Drosophila melanogaster)
Utp25 [nucleoplasm]
(Mus musculus)
Utp25 [nucleoplasm]
(Rattus norvegicus)
DIEXF [nucleoplasm]
(Caenorhabditis elegans)
DIEXF [nucleoplasm]
(Dictyostelium discoideum)
DIEXF [nucleoplasm]
(Gallus gallus)
DIEXF [nucleoplasm]
(Plasmodium falciparum)
utp25 [nucleoplasm]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_055203.4
OpenTargets
ENSG00000117597
HPA
ENSG00000117597-UTP25
GeneCards
Q68CQ4
Ensembl
ENST00000491415
,
ENSG00000117597
,
ENSP00000419005
PRO
Q68CQ4
Pharos - Targets
Q68CQ4
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96T51 RUFY1
3
p-Y389,400-RUFY1 [cytosol]
(R-HSA-8871352)
RUFY1 [cytosol]
(R-HSA-8871374)
p-Y389,400-RUFY1 [early endosome membrane]
(R-HSA-5215951)
0.742
5
UniProt:Q96CW1 AP2M1
6
AP2M1 [plasma membrane]
(R-HSA-167585)
AP2M1 [lysosomal membrane]
(R-HSA-196144)
AP2M1 [cytosol]
(R-HSA-182227)
AP2M1 [clathrin-coated endocytic vesicle membrane]
(R-HSA-2130423)
AP2M1 [endolysosome membrane]
(R-HSA-6784828)
p-T156 AP2M1 [cytosol]
(R-HSA-8856805)
0.666
7
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