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DHX37 [nucleoplasm]
Stable Identifier
R-HSA-6790668
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Probable ATP-dependent RNA helicase DHX37 ecNumber3.6.4.13/ecNumber, DHX37_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the nucleus and cytosol (Homo sapiens)
Major pathway of rRNA processing in the nucleolus and cytosol (Homo sapiens)
21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA (Homo sapiens)
18SE pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
DHX37 [nucleoplasm] (Homo sapiens)
21S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
DHX37 [nucleoplasm] (Homo sapiens)
30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA (Homo sapiens)
21S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
DHX37 [nucleoplasm] (Homo sapiens)
30S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
DHX37 [nucleoplasm] (Homo sapiens)
45S pre-rRNA is nucleolytically processed at site 2 (site 2b) to yield 30S pre-rRNA and 32S pre-rRNA (Homo sapiens)
30S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
DHX37 [nucleoplasm] (Homo sapiens)
45S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
DHX37 [nucleoplasm] (Homo sapiens)
47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA (Homo sapiens)
45S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
DHX37 [nucleoplasm] (Homo sapiens)
47S pre-rRNA:SSU processome [nucleoplasm] (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
DHX37 [nucleoplasm] (Homo sapiens)
rRNA modification in the nucleus and cytosol (Homo sapiens)
EMG1 of the SSU processome methylates pseudouridine-1248 of 18S rRNA yielding N(1)-methylpseudouridine-1248 (Homo sapiens)
SSU Processome [nucleoplasm] (Homo sapiens)
DHX37 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8IY37 DHX37
Gene Names
DHX37, DDX37, KIAA1517
Chain
chain:1-1157
Reference Genes
BioGPS Gene:57647 DHX37
COSMIC (genes):DHX37 DHX37
CTD Gene:57647 DHX37
dbSNP Gene:57647 DHX37
ENSEMBL:ENSG00000150990 DHX37
ENSEMBL_homo_sapiens_GENE:ENSG00000150990.9 DHX37
HGNC:17210 DHX37
KEGG Gene (Homo sapiens):57647 DHX37
Monarch:57647 DHX37
NCBI Gene:57647 DHX37
OMIM:617362 DHX37
UCSC:Q8IY37 DHX37
Reference Transcript
RefSeq:NM_032656.3 DHX37
Other Identifiers
11755647_a_at
16772197
223364_PM_s_at
223364_s_at
223365_PM_at
223365_at
3476795
3476797
3476798
3476799
3476800
3476802
3476804
3476805
3476807
3476809
3476810
3476812
3476813
3476817
3476818
3476819
3476820
3476821
3476822
3476823
3476824
3476825
3476826
3476828
3476829
3476830
3476831
3476834
3476835
3476836
3476837
3476838
3476840
3476841
3476842
57647
58500_at
69913_at
7967588
A_23_P13914
GE88175
GO:0000166
GO:0000462
GO:0003676
GO:0003723
GO:0003724
GO:0003824
GO:0004386
GO:0005515
GO:0005524
GO:0005634
GO:0005635
GO:0005654
GO:0005730
GO:0005737
GO:0007420
GO:0016020
GO:0016787
GO:0016887
GO:0022414
GO:0031965
GO:0032040
GO:0034511
GO:0042254
GO:0042255
GO:0042274
GO:0043226
GO:0048856
GO:0140098
GO:0140657
GO:2000020
HMNXSV003026067
ILMN_1805742
ILMN_2192683
PH_hs_0005963
TC12002105.hg
g13325300_3p_a_at
g13325300_3p_at
g13325300_3p_x_at
Participates
as a component of
SSU Processome [nucleoplasm] (Homo sapiens)
Inferred To
dhx37 [nucleoplasm]
(Dictyostelium discoideum)
Dhx37 [nucleoplasm]
(Mus musculus)
Dhx37 [nucleoplasm]
(Rattus norvegicus)
DHX37 [nucleoplasm]
(Bos taurus)
DHX37 [nucleoplasm]
(Caenorhabditis elegans)
DHX37 [nucleoplasm]
(Canis familiaris)
DHX37 [nucleoplasm]
(Drosophila melanogaster)
DHX37 [nucleoplasm]
(Gallus gallus)
DHX37 [nucleoplasm]
(Plasmodium falciparum)
DHX37 [nucleoplasm]
(Saccharomyces cerevisiae)
DHX37 [nucleoplasm]
(Schizosaccharomyces pombe)
DHX37 [nucleoplasm]
(Sus scrofa)
Cross References
RefSeq
NP_116045.2
OpenTargets
ENSG00000150990
HPA
ENSG00000150990-DHX37
GeneCards
Q8IY37
Ensembl
ENSP00000311135
,
ENST00000308736
,
ENSG00000150990
PRO
Q8IY37
Pharos - Targets
Q8IY37
Orphanet
29246
PDB
7MQA
HMDB Protein
HMDBP11702
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P0DTC9 N
13
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane]
(R-COV-9729325)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus]
(R-COV-9729339)
N [plasma membrane]
(R-COV-9694356)
SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol]
(R-COV-9756489)
N [cytosol]
(R-COV-9694300)
p-S188,206-N [cytosol]
(R-COV-9729324)
p-8S-N [cytosol]
(R-COV-9729335)
p-8S,2T-N [cytosol]
(R-COV-9729277)
p-11S,2T-N [cytosol]
(R-COV-9729264)
p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729308)
ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729275)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9729341)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729340)
0.527
2
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