Reactome | MPHOSPH10 [nucleoplasm]

MPHOSPH10 [nucleoplasm]

Stable Identifier

R-HSA-6790661

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

U3 small nucleolar ribonucleoprotein protein MPP10, MPP10_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O00566 MPHOSPH10

Gene Names

MPHOSPH10, MPP10

Chain

chain:1-681

Reference Genes

BioGPS Gene:10199 MPHOSPH10

COSMIC (genes):MPHOSPH10 MPHOSPH10

CTD Gene:10199 MPHOSPH10

dbSNP Gene:10199 MPHOSPH10

ENSEMBL:ENSG00000124383 MPHOSPH10

ENSEMBL_homo_sapiens_GENE:ENSG00000124383.11 MPHOSPH10

HGNC:7213 MPHOSPH10

KEGG Gene (Homo sapiens):10199 MPHOSPH10

Monarch:10199 MPHOSPH10

NCBI Gene:10199 MPHOSPH10

OMIM:605503 MPHOSPH10

UCSC:O00566 MPHOSPH10

Reference Transcript

RefSeq:NM_005791.2 MPHOSPH10

Other Identifiers

10199

11743866_at

16881274

212885_PM_at

212885_at

2488080

2488081

2488082

2488083

2488084

2488086

2488087

2488088

2488090

2488091

2488093

2488095

2488096

33797_at

3585682

3586449

3612553

3613638

3616666

4039245

8042588

A_23_P5586

GE62981

GO:0000375

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005730

GO:0005732

GO:0006364

GO:0006396

GO:0008380

GO:0030490

GO:0032040

GO:0034457

GO:0042254

GO:0042274

GO:0043226

GO:1990904

HMNXSV003055361

Hs.201676.0.S1_3p_at

ILMN_1652085

ILMN_2229950

PH_hs_0011834

TC02000428.hg

Participates

as a component of

MPP10 complex [nucleoplasm] (Homo sapiens)

Inferred To

Mphosph10 [nucleoplasm] (Mus musculus)

Mphosph10 [nucleoplasm] (Rattus norvegicus)

Dmel\CG13097 [nucleoplasm] (Drosophila melanogaster)

MPHOSPH10 [nucleoplasm] (Bos taurus)

MPHOSPH10 [nucleoplasm] (Caenorhabditis elegans)

MPHOSPH10 [nucleoplasm] (Canis familiaris)

MPHOSPH10 [nucleoplasm] (Gallus gallus)

MPHOSPH10 [nucleoplasm] (Plasmodium falciparum)

MPHOSPH10 [nucleoplasm] (Sus scrofa)

mpp10 [nucleoplasm] (Dictyostelium discoideum)

mpp10 [nucleoplasm] (Schizosaccharomyces pombe)

MPP10 [nucleoplasm] (Saccharomyces cerevisiae)

Cross References

RefSeq

NP_005782.1

OpenTargets

ENSG00000124383

HPA

ENSG00000124383-MPHOSPH10

GeneCards

O00566

Ensembl

ENSG00000124383, ENST00000244230, ENSP00000244230

PRO

O00566

Pharos - Targets

O00566

PDB

7MQA, 7MQ8, 7MQ9

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P06748 NPM1	11	monoSUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039) polySUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm] (R-HSA-9725010) NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol] (R-HSA-9730703) NPM1(1-117)-ALK(1068-1620) fusion [cytosol] (R-HSA-9730697) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9699861) NPM1(1-117)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699834) NPM1 [granular component] (R-HSA-9017702) NPM1 [nucleoplasm] (R-HSA-606320) NPM1 [cytosol] (R-HSA-3008211) p-S4-NPM1 [cytosol] (R-HSA-6801679)	0.615	3
UniProt:P62136 PPP1CA	1	PPP1CA [cytosol] (R-HSA-163525)	0.592	2
UniProt:Q13895 BYSL	2	BYSL [nucleoplasm] (R-HSA-6791526) BYSL [cytosol] (R-HSA-6791518)	0.556	3
UniProt:P15880 RPS2	3	RPS2 [nucleoplasm] (R-HSA-6790655) Me2aR-RPS2 [cytosol] (R-HSA-8879138) RPS2 [cytosol] (R-HSA-72347)	0.527	3
UniProt:P0DTC9 N	13	SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane] (R-COV-9729325) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus] (R-COV-9729339) N [plasma membrane] (R-COV-9694356) SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol] (R-COV-9756489) N [cytosol] (R-COV-9694300) p-S188,206-N [cytosol] (R-COV-9729324) p-8S-N [cytosol] (R-COV-9729335) p-8S,2T-N [cytosol] (R-COV-9729277) p-11S,2T-N [cytosol] (R-COV-9729264) p-11S,2T-metR95,177-N [cytosol] (R-COV-9729308) ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729275) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9729341) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729340)	0.527	2
UniProt:P62753 RPS6	4	RPS6 [nucleoplasm] (R-HSA-6790606) 3OHR147-RPS6 [cytosol] (R-HSA-9629876) p-5S-RPS6 [cytosol] (R-HSA-165727) RPS6 [cytosol] (R-HSA-72381)	0.483	4

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