Reactome | ZEB1 [nucleoplasm]

ZEB1 [nucleoplasm]

Stable Identifier

R-HSA-6789836

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Zinc finger E-box-binding homeobox 1, ZEB1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P37275 ZEB1

Gene Names

ZEB1, AREB6, TCF8

Chain

chain:1-1124

Reference Genes

BioGPS Gene:6935 ZEB1

COSMIC (genes):ZEB1 ZEB1

CTD Gene:6935 ZEB1

dbSNP Gene:6935 ZEB1

ENSEMBL:ENSG00000148516 ZEB1

ENSEMBL_homo_sapiens_GENE:ENSG00000148516.23 ZEB1

HGNC:11642 ZEB1

KEGG Gene (Homo sapiens):6935 ZEB1

Monarch:6935 ZEB1

NCBI Gene:6935 ZEB1

OMIM:189909 ZEB1

UCSC:P37275 ZEB1

Reference Transcript

Other Identifiers

11721545_x_at

11721546_s_at

11721547_s_at

11734686_x_at

11749136_x_at

11749644_s_at

11758473_s_at

16703715

210875_PM_s_at

210875_s_at

212758_PM_s_at

212758_s_at

212764_PM_at

212764_at

239952_PM_at

239952_at

3241318

3241319

3241320

3241360

3241368

3241369

3241371

3241374

3241378

3241379

3241381

3241382

3241383

3241384

3241385

3241386

3241387

3241388

3241389

33440_at

61486_at

6935

7926916

A_14_P102704

A_14_P129718

A_23_P202013

A_33_P3374723

A_33_P3640690

GE563654

GO:0000122

GO:0000785

GO:0000978

GO:0000981

GO:0001227

GO:0002376

GO:0003677

GO:0003682

GO:0003690

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005829

GO:0006351

GO:0006355

GO:0006357

GO:0007389

GO:0007399

GO:0007417

GO:0008270

GO:0008283

GO:0010464

GO:0010839

GO:0014823

GO:0017015

GO:0023052

GO:0030154

GO:0030857

GO:0030900

GO:0031667

GO:0033081

GO:0043226

GO:0043565

GO:0043616

GO:0045602

GO:0045666

GO:0045892

GO:0045944

GO:0046872

GO:0048513

GO:0048596

GO:0048598

GO:0048704

GO:0048752

GO:0048856

GO:0050673

GO:0050680

GO:0051150

GO:0051216

GO:0070888

GO:0071230

GO:0071560

GO:0090103

GO:0140110

HMNXSV003039633

Hs.104372.0.A1_3p_at

Hs.232068.2.A1_3p_s_at

Hs.232068.2.A2_3p_at

ILMN_1762231

PH_hs_0012717

g529172_3p_a_at

Participates

as a member of

STAT3-upregulated nuclear proteins [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001167567.1, NP_001167565.1, NP_001167566.1, NP_110378.3, NP_001167564.1, NP_001121600.1

OpenTargets

ENSG00000148516

GeneCards

P37275

HPA

ENSG00000148516-ZEB1

Ensembl

ENSP00000391612, ENST00000446923, ENSP00000444891, ENST00000424869, ENSP00000452787, ENSG00000148516, ENST00000320985, ENSP00000415961, ENSP00000319248, ENST00000542815, ENST00000560721

PRO

P37275

Pharos - Targets

P37275

Orphanet

15739

PDB

2E19

HMDB Protein

HMDBP10917

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13363 CTBP1	3	monoSUMO1-K428-CTBP1 [nucleoplasm] (R-HSA-3108200) polySUMO2,3-K428-CTBP1 [nucleoplasm] (R-HSA-3108226) CTBP1 [nucleoplasm] (R-HSA-212372)	0.859	12
UniProt:Q92769 HDAC2	2	monoSUMO1-K462-HDAC2 [nucleoplasm] (R-HSA-4615958) HDAC2 [nucleoplasm] (R-HSA-205135)	0.527	2