Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
LIPA [lysosomal lumen]
Stable Identifier
R-HSA-6788929
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal lumen
Synonyms
Lysosomal acid lipase/cholesteryl ester hydrolase, LICH_HUMAN
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
Plasma lipoprotein assembly, remodeling, and clearance (Homo sapiens)
Plasma lipoprotein clearance (Homo sapiens)
LDL clearance (Homo sapiens)
LIPA hydrolyses sterol esters to sterols and fatty acids (Homo sapiens)
LIPA [lysosomal lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P38571 LIPA
Gene Names
LIPA
Chain
signal peptide:1-27, propeptide:28-76, chain:77-399
Reference Genes
BioGPS Gene:3988 LIPA
COSMIC (genes):LIPA LIPA
CTD Gene:3988 LIPA
dbSNP Gene:3988 LIPA
ENSEMBL:ENSG00000107798 LIPA
ENSEMBL_homo_sapiens_GENE:ENSG00000107798.18 LIPA
HGNC:6617 LIPA
KEGG Gene (Homo sapiens):3988 LIPA
Monarch:3988 LIPA
NCBI Gene:3988 LIPA
OMIM:613497 LIPA
UCSC:P38571 LIPA
Reference Transcript
RefSeq:NM_001127605.2 LIPA
RefSeq:NM_001288979.1 LIPA
RefSeq:NM_000235.3 LIPA
Other Identifiers
11741555_s_at
11745775_a_at
201847_PM_at
201847_at
3299586
3299587
3299588
3299589
3299590
3299591
3299594
3299595
3299596
3299597
3299598
3299599
3299600
3299610
3299611
3299612
3299617
3299646
3299648
38745_at
3988
7934920
A_23_P97860
GE60021
GO:0000278
GO:0000902
GO:0001523
GO:0001650
GO:0001889
GO:0001935
GO:0002021
GO:0002244
GO:0002376
GO:0002526
GO:0002536
GO:0003824
GO:0004771
GO:0005634
GO:0005654
GO:0005730
GO:0005764
GO:0005773
GO:0005829
GO:0005975
GO:0006006
GO:0006091
GO:0006096
GO:0006629
GO:0006631
GO:0006638
GO:0006641
GO:0006695
GO:0006754
GO:0006766
GO:0006776
GO:0006897
GO:0006954
GO:0007005
GO:0007040
GO:0007264
GO:0008203
GO:0008283
GO:0008333
GO:0008340
GO:0009409
GO:0009410
GO:0010467
GO:0010878
GO:0012501
GO:0016042
GO:0016125
GO:0016192
GO:0016298
GO:0016787
GO:0016788
GO:0019915
GO:0022600
GO:0023052
GO:0030097
GO:0030099
GO:0030154
GO:0030163
GO:0030217
GO:0030301
GO:0030324
GO:0030421
GO:0031929
GO:0033028
GO:0033189
GO:0033344
GO:0033993
GO:0034383
GO:0035726
GO:0042098
GO:0042159
GO:0042391
GO:0043202
GO:0043226
GO:0043231
GO:0044255
GO:0048536
GO:0048539
GO:0048771
GO:0048856
GO:0048871
GO:0048872
GO:0048873
GO:0050673
GO:0050862
GO:0051881
GO:0055086
GO:0055088
GO:0060612
GO:0060837
GO:0061519
GO:0070231
GO:0070341
GO:0071830
GO:0071838
GO:0072576
GO:0097009
GO:0097384
GO:0140354
GO:0140962
GO:1901135
GO:1901355
GO:1903409
GO:1990845
HMNXSV003012086
ILMN_1718063
PH_hs_0004818
U04285_s_at
Z31690_s_at
g4557720_3p_at
Inferred To
LIPA [lysosomal lumen]
(Bos taurus)
LIPA [lysosomal lumen]
(Canis familiaris)
LIPA [lysosomal lumen]
(Gallus gallus)
LIPA [lysosomal lumen]
(Sus scrofa)
Lipa [lysosomal lumen]
(Mus musculus)
Lipa [lysosomal lumen]
(Rattus norvegicus)
Cross References
RefSeq
NP_001121077.1
,
NP_001275908.1
,
NP_000226.2
OpenTargets
ENSG00000107798
ZINC - Substances
LICH_HUMAN
ZINC target
P38571
PRO
P38571
PDB
6V7N
HPA
ENSG00000107798-LIPA
GeneCards
P38571
Ensembl
ENST00000371837
,
ENST00000336233
,
ENSP00000360903
,
ENSP00000337354
,
ENSG00000107798
Pharos - Targets
P38571
ZINC - Predictions - Purchasable
LICH_HUMAN
Orphanet
16359
HMDB Protein
HMDBP00227
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text