HYKK phosphorylates 5HLYS

Stable Identifier
R-HSA-6788611
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
(5R)-5-hydroxy-L-lysine + GTP => (5R)-5-phosphooxy-L-lysine + GDP + H(+)
ReviewStatus
5/5
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HYKK phosphorylates 5HLYS
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Hydroxylysine kinase (HYKK) phosphorylates 5-hydroxylysine (5HLYS), derived from food and collagen breakdown, to 5-phosphonooxy-L-lysine (5PHL) using GTP as the preferential phosphate donor (Veiga-da-Cunha et al. 2012).
Literature References
PubMed ID Title Journal Year
22241472 Molecular identification of hydroxylysine kinase and of ammoniophospholyases acting on 5-phosphohydroxy-L-lysine and phosphoethanolamine

Veiga-da-Cunha, M, Hadi, F, Balligand, T, Stroobant, V, Van Schaftingen, E

J. Biol. Chem. 2012
Participants
Input
Output
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as an event of
Catalyst Activity

hydroxylysine kinase activity of HYKK [mitochondrial matrix]

Physical Entity
HYKK [mitochondrial matrix] (Homo sapiens)
Activity
hydroxylysine kinase activity (GO:0047992)
Orthologous Events
HYKK phosphorylates 5HLYS (Bos taurus)
HYKK phosphorylates 5HLYS (Canis familiaris)
HYKK phosphorylates 5HLYS (Danio rerio)
HYKK phosphorylates 5HLYS (Drosophila melanogaster)
HYKK phosphorylates 5HLYS (Gallus gallus)
HYKK phosphorylates 5HLYS (Mus musculus)
HYKK phosphorylates 5HLYS (Rattus norvegicus)
HYKK phosphorylates 5HLYS (Sus scrofa)
HYKK phosphorylates 5HLYS (Xenopus tropicalis)
Cross References
RHEA
Authored
Jassal, B  (2015-07-23)
Reviewed
D'Eustachio, P  (2015-09-14)
D'Eustachio, P  (2024-11-08)
Created
Jassal, B  (2015-07-23)
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