FUOM isomerises alpha-Fuc to beta-Fuc

Stable Identifier
R-HSA-6787677
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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FUOM isomerises alpha-Fuc to beta-Fuc
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
L-Fucose (6-deoxy-L-galactose) exists in two different forms, alpha-L-fucose (29.5%) and beta-L-fucose (70.5%). The beta-form is metabolised through the salvage pathway to ultimately form GDP-fucose. Fucose mutarotase (FUOM) is involved in the anomeric conversions of monosaccharides, converting alpha-Fuc to beta-Fuc (Timson & Reece 2003).
Literature References
PubMed ID Title Journal Year
12753898 Identification and characterisation of human aldose 1-epimerase

Reece, RJ, Timson, DJ

FEBS Lett. 2003
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Output
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as an event of
Catalyst Activity

racemase and epimerase activity, acting on carbohydrates and derivatives of FUOM dimer [cytosol]

Physical Entity
FUOM dimer [cytosol] (Homo sapiens)
Activity
racemase and epimerase activity, acting on carbohydrates and derivatives (GO:0016857)
Orthologous Events
FUOM isomerises alpha-Fuc to beta-Fuc (Bos taurus)
FUOM isomerises alpha-Fuc to beta-Fuc (Canis familiaris)
FUOM isomerises alpha-Fuc to beta-Fuc (Danio rerio)
FUOM isomerises alpha-Fuc to beta-Fuc (Mus musculus)
FUOM isomerises alpha-Fuc to beta-Fuc (Rattus norvegicus)
FUOM isomerises alpha-Fuc to beta-Fuc (Sus scrofa)
Cross References
Rhea
Authored
Jassal, B  (2015-07-15)
Reviewed
D'Eustachio, P  (2015-09-14)
Created
Jassal, B  (2015-07-15)
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